Antimicrobial, Thermoanalytical and Viscometric Studies of Metal Based Schiff Base Polymer

被引:0
作者
Mughal, Moina Akhtar [1 ]
Mughal, Akhtar [2 ]
Memon, Ghulam Zuhra [1 ]
Khuhawar, Mohammad Yar [3 ]
Memon, Nusrat Naeem [1 ]
机构
[1] Univ Sindh, Dr MA Kazi Inst Chem, Jamshoro, Sindh, Pakistan
[2] Univ Sindh, Inst Phys, Jamshoro, Sindh, Pakistan
[3] Univ Sindh, Inst Adv Res Studies Chem Sci, Jamshoro, Sindh, Pakistan
来源
JOURNAL OF THE CHEMICAL SOCIETY OF PAKISTAN | 2013年 / 35卷 / 06期
关键词
antimicrobial; viscosity; Schiff base; PMBPCPR; TGA; CARBONIC-ANHYDRASE INHIBITORS; COMPLEXES;
D O I
暂无
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
This study examines the synthesis, characterization, viscosity, thermal behavior and antimicrobial studies of copper(II) and nickel(II), complexes of a synthesized monomer 5,5-methylene bis(2'-pyridinecarboxaldehyde) (MBPC) and a Schiff base polymer poly-5,5-methylene bis (2-pyridinecarboxaldehyde) 1,3-propylenedimine (PMBPCPR). The monomer, polymeric ligand and poly metal complexes (PMBPCPRCu) and (PMBPCPRNi) were characterized by C.H.N analysis, FT-IR, UV -Vis spectroscopy, viscometery thermogravimetric (TGA) and differential thermogravimetry (DTA). The monomer MBPC was prepared by the reaction of 2-pyridinecarboxaldehyde with 1, 3, 5-trioxane in the presence of acetic acid and sulphuric acid. The polymeric ligand was prepared by polycondensation of monomer with 1,3-propylenediamine. The biological studies of compounds revealed that they possessed significant antibacterial and antifungal properties, against Micrococcus flavus, Staphylococcus aureus, Bacillus Cirroflgellosus, Shigella flexneri, Escherichia Coli, Candida albicans, Aspergillus flavus, and A. Niger.
引用
收藏
页码:1535 / 1542
页数:8
相关论文
共 30 条
[11]  
2-G
[12]   A new class of organic-inorganic hybrid materials:: Hydrothermal synthesis and structural characterization of bimetallic organophosphonate oxide phases of the Mo/Cu/O/RPO32- family [J].
Finn, RC ;
Zubieta, J .
INORGANIC CHEMISTRY, 2001, 40 (11) :2466-+
[13]   Co-ordination polymers [J].
Kaliyappan, T ;
Kannan, P .
PROGRESS IN POLYMER SCIENCE, 2000, 25 (03) :343-370
[14]   CHELATING POLYMERS AND RELATED SUPPORTS FOR SEPARATION AND PRECONCENTRATION OF TRACE-METALS [J].
KANTIPULY, C ;
KATRAGADDA, S ;
CHOW, A ;
GESSER, HD .
TALANTA, 1990, 37 (05) :491-517
[15]   Synthesis and characterization of some new Schiff base polymers [J].
Khuhawar, MY ;
Mughal, MA ;
Channar, AH .
EUROPEAN POLYMER JOURNAL, 2004, 40 (04) :805-809
[16]   Syntheses and thermoanalytical studies of some Schiff base polymers derived from 5,5′-methylene bis(2-hydroxyacetophenone) [J].
Khuhawar, MY ;
Channar, AH ;
Shah, SW .
EUROPEAN POLYMER JOURNAL, 1998, 34 (01) :133-135
[17]   SYNTHESES AND CHARACTERIZATION OF NEW SCHIFF-BASE POLYMERS AND THEIR COPPER(II) AND NICKEL(II) CHELATES [J].
KHUHAWAR, MY ;
CHANNAR, AH .
JOURNAL OF MACROMOLECULAR SCIENCE-PURE AND APPLIED CHEMISTRY, 1995, A32 :523-530
[18]   Metal complexes as enzyme inhibitors [J].
Louie, AY ;
Meade, TJ .
CHEMICAL REVIEWS, 1999, 99 (09) :2711-2734
[19]   HEAT STABILITY STUDIES ON CHELATES FROM SCHIFF BASES OF SALICYLALDEHYDE DERIVATIVES [J].
MARVEL, CS ;
TARKOY, N .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1957, 79 (22) :6000-6002
[20]  
Moghal M. A., 2003, THESIS, P1