Imidazolium Zwitterionic Molten Salt: An Efficient Organocatalyst under Neat Conditions at Room Temperature for the Synthesis of Dipyrromethanes as well as Bis(indolyl)methanes

被引：28

作者：

Chatterjee, Rana ^{[1
]}

Mahato, Sachinta ^{[1
]}

Santra, Sougata ^{[2
]}

Zyryanov, Grigory V. ^{[2
,3
]}

Hajra, Alakananda ^{[1
]}

Majee, Adinath ^{[1
]}

机构：

[1] Visva Bharati A Cent Univ, Dept Chem, Santini Ketan 731235, W Bengal, India

[2] Ural Fed Univ, Dept Organ & Biomol Chem, Inst Chem Engn, 19 Mira Str, Ekaterinburg 620002, Russia

[3] Russian Acad Sci, I Ya Postovskiy Inst Organ Synth, Ural Div, 22 S Kovalevskoy Str, Ekaterinburg 620219, Russia

来源：

CHEMISTRYSELECT | 2018年 / 3卷 / 21期

基金：

俄罗斯科学基金会;

关键词：

bis(indolyl)methanes; dipyrromethanes; room temperature; solvent-free; zwitterionic molten salt; NONREARRANGED MONOTERPENOID UNIT; SIMPLE INDOLE ALKALOIDS; SOLVENT-FREE CONDITIONS; CHIRAL IONIC LIQUIDS; CARBONYL-COMPOUNDS; MESOSUBSTITUTED DIPYRROMETHANES; REGIOSELECTIVE SYNTHESIS; CATALYTIC APPLICATION; BIS-INDOLYLMETHANES; MEDIATED SYNTHESIS;

D O I：

10.1002/slct.201800227

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

An imidazole-based zwitterionic-salt, 4-(3-methylimidazolium)butane sulfonate (MBS), has been found to be an efficient organocatalyst for the synthesis of dipyrromethanes as well as bis(indolyl)methanes at room temperature under solvent-free conditions (neat) in high yields. The reaction procedure is very simple and a large variety of aldehydes have been examined under similar conditions for indoles and pyrroles. The catalytic reaction proceeded very smoothly and showed high chemoselectivity. Clean reaction, ease of product isolation/purification, easily accessible reactants, metal and solvent-free and environmentally friendly reaction conditions are the notable advantages of the present methodology.

引用

页码：5843 / 5847

页数：5

共 69 条

[61] The reaction of N-tosyl imines with heteroaromatic compounds: a new access to triheteroarylmethanes [J].