Condensation of 1-substituted 1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-one derivatives with aromatic aldehydes

被引：0

作者：

Sackus, A ^{[1
]}

Amankaviciene, V ^{[1
]}

机构：

[1] Kaunas Univ Technol, Fac Chem Technol, Dept Organ Chem, LT-3028 Kaunas, Lithuania

来源：

KHIMIYA GETEROTSIKLICHESKIKH SOEDINENII | 2002年 / 07期

关键词：

9a-(2-phenylethyl)-1,2,3,9a-tetrallydro-9H-imidazo[1,2-a]indol-2-one; 1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-one; alkylation; condensation;

D O I：

暂无

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Condensation of 1-alkyl-, 1-allyl-, and 1-benzyl-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-ones with benzaldehydes in acetic acid and the following treatment of the reaction mixture with potassium hydroxide afforded 1-substituted 9a-(2-phenylethenyl)-1,2,3,9a-tetrahydro-9H-imidazo[1,2-a]indol-2-one derivatives. 1-Methyl- and 1-ethyl-9a-[2-(4-dimethylaminophenyl)ethenyl]-1,2,3,9a-tetrahydro-9H-imidazo[1, 2-a] indol-2 -ones were synthesized by alkylation of 9a-[2-(4-dimethylaminophenyl)ethenyl]-1,2,3.9a-tetrahydro-9H-imidazo[1,2-a]indol-2-one with methyl and ethyl iodides in DMF in the presence of a strong base.

引用

页码：931 / 936

页数：6

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