Chemoenzymatic asymmetric synthesis of harzia lactone A stereomers

被引：14

作者：

Kumar, Abha N. ^{[1
]}

Bhatt, Suchitra ^{[1
]}

Chattopadhyay, Subrata ^{[1
]}

机构：

[1] Bhabha Atom Res Ctr, Bioorgan Div, Bombay 400085, Maharashtra, India

来源：

TETRAHEDRON-ASYMMETRY | 2009年 / 20卷 / 02期

关键词：

ABSOLUTE STEREOCHEMISTRY; HIGH ENANTIOSELECTIVITY; HARZIALACTONE-A; D-GLUCOSE; DIHYDROXYLATION; ASSIGNMENT; OXIDATION; ALDEHYDES;

D O I：

10.1016/j.tetasy.2009.01.009

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A facile chemoenzymatic synthesis of the harzia lactone A enantiomers was developed. A lipase-catalyzed acylation and an enantio-controlled substrate and reagent-con trol led Sharpless' asymmetric dihydroxylation are the key features of the synthesis. (C) 2009 Elsevier Ltd. All rights reserved.

引用

页码：205 / 209

页数：5

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