The Young and the Restless: Regulation of Adult Neurogenesis by Wnt Signaling

被引:11
|
作者
Wu, Melody V. [1 ,4 ]
Hen, Rene [1 ,2 ,3 ,4 ]
机构
[1] Columbia Univ, Dept Psychiat, New York, NY 10032 USA
[2] Columbia Univ, Dept Neurosci, New York, NY 10032 USA
[3] Columbia Univ, Dept Pharmacol, New York, NY 10032 USA
[4] New York State Psychiat Inst & Hosp, Div Integrat Neurosci, New York, NY 10032 USA
关键词
D O I
10.1016/j.stem.2013.01.013
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Wnt signaling plays a critical role in developmental and adult neurogenesis. In this issue of Cell Stem Cell, Jang et al. (2013) and Seib et al. (2013) show how age and neuronal activity regulate adult hippocampal neurogenesis by inhibiting or activating, respectively, distinct components of the Wnt signaling machinery.
引用
收藏
页码:139 / 140
页数:2
相关论文
共 50 条
  • [31] Neuroglobin promotes neurogenesis through Wnt signaling pathway
    Yu, Zhanyang
    Cheng, Chongjie
    Liu, Yu
    Liu, Ning
    Lo, Eng H.
    Wang, Xiaoying
    CELL DEATH & DISEASE, 2018, 9
  • [32] The Role of Notch Signaling in Adult Neurogenesis
    Imayoshi, Itaru
    Kageyama, Ryoichiro
    MOLECULAR NEUROBIOLOGY, 2011, 44 (01) : 7 - 12
  • [33] Wnt pathway dynamics during neurogenesis in the adult hippocampus
    Schafer, S. T.
    ACTA PHYSIOLOGICA, 2017, 219 : 19 - 19
  • [34] Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling
    Omer Durak
    Fan Gao
    Yea Jin Kaeser-Woo
    Richard Rueda
    Anthony J Martorell
    Alexi Nott
    Carol Y Liu
    L Ashley Watson
    Li-Huei Tsai
    Nature Neuroscience, 2016, 19 : 1477 - 1488
  • [35] Chd8 mediates cortical neurogenesis via transcriptional regulation of cell cycle and Wnt signaling
    Durak, Omer
    Gao, Fan
    Kaeser-Woo, Yea Jin
    Rueda, Richard
    Martorell, Anthony J.
    Nott, Alexi
    Liu, Carol Y.
    Watson, L. Ashley
    Tsai, Li-Huei
    NATURE NEUROSCIENCE, 2016, 19 (11) : 1477 - 1488
  • [36] Regulation of Wnt signaling by protocadherins
    Mah, Kar Men
    Weiner, Joshua A.
    SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY, 2017, 69 : 158 - 171
  • [37] Androgen regulation by Wnt signaling
    不详
    PROSTATE CANCER AND PROSTATIC DISEASES, 2006, 9 (03) : 203 - 203
  • [38] Function and regulation of neurogenesis in the adult brain
    Gage, F. H.
    JOURNAL OF NEUROCHEMISTRY, 2009, 110 : 2 - 2
  • [39] Regulation and function of neurogenesis in the adult hippocampus
    Gage, FH
    FASEB JOURNAL, 2001, 15 (04): : A404 - A404
  • [40] Epigenetic regulation of neurogenesis in the adult hippocampus
    M Covic
    E Karaca
    D C Lie
    Heredity, 2010, 105 : 122 - 134