The Young and the Restless: Regulation of Adult Neurogenesis by Wnt Signaling

被引:11
|
作者
Wu, Melody V. [1 ,4 ]
Hen, Rene [1 ,2 ,3 ,4 ]
机构
[1] Columbia Univ, Dept Psychiat, New York, NY 10032 USA
[2] Columbia Univ, Dept Neurosci, New York, NY 10032 USA
[3] Columbia Univ, Dept Pharmacol, New York, NY 10032 USA
[4] New York State Psychiat Inst & Hosp, Div Integrat Neurosci, New York, NY 10032 USA
关键词
D O I
10.1016/j.stem.2013.01.013
中图分类号
Q813 [细胞工程];
学科分类号
摘要
Wnt signaling plays a critical role in developmental and adult neurogenesis. In this issue of Cell Stem Cell, Jang et al. (2013) and Seib et al. (2013) show how age and neuronal activity regulate adult hippocampal neurogenesis by inhibiting or activating, respectively, distinct components of the Wnt signaling machinery.
引用
收藏
页码:139 / 140
页数:2
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