Diverse Roles of Prostaglandins in Blastocyst Implantation

被引:46
作者
Salleh, Naguib [1 ]
机构
[1] Univ Malaya, Fac Med, Dept Physiol, Kuala Lumpur 50603, Malaysia
关键词
ENDOMETRIAL STROMAL CELLS; LEUKEMIA INHIBITORY FACTOR; PERIIMPLANTATION MOUSE UTERUS; ACTIVATED-RECEPTOR-DELTA; NITRIC-OXIDE SYNTHASE; BINDING PROTEIN-BETA; GROWTH-FACTOR; DIFFERENTIAL EXPRESSION; CYCLIC-AMP; PROSTACYCLIN SYNTHASE;
D O I
10.1155/2014/968141
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
Prostaglandins (PGs), derivatives of arachidonic acid, play an indispensable role in embryo implantation. PGs have been reported to participate in the increase in vascular permeability, stromal decidualization, blastocyst growth and development, leukocyte recruitment, embryo transport, trophoblast invasion, and extracellular matrix remodeling during implantation. Deranged PGs syntheses and actions will result in implantation failure. This review summarizes up-to-date literatures on the role of PGs in blastocyst implantation which could provide a broad perspective to guide further research in this field.
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页数:11
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