A Key Role of Insulin Receptors in Memory

被引：54

作者：

De Felice, Fernanda G. ^{[1
,2
,3
]}

Benedict, Christian ^{[4
]}

机构：

[1] Univ Fed Rio de Janeiro, Inst Med Biochem Leopoldo Meis, Rio De Janeiro, Brazil

[2] DOr Inst Res & Educ, Rio De Janeiro, Brazil

[3] Queens Univ, Dept Biomed & Mol Sci, Kingston, ON, Canada

[4] Uppsala Univ, Dept Neurosci, Uppsala, Sweden

来源：

DIABETES | 2015年 / 64卷 / 11期

关键词：

CENTRAL-NERVOUS-SYSTEM; ALZHEIMERS-DISEASE; INTRANASAL INSULIN; RESISTANCE; BRAIN; DYSFUNCTION; IGF-1;

D O I：

10.2337/dbi15-0011

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：3653 / 3655

页数：3

共 19 条

[1]

Banting FG, 1922, J LAB CLIN MED, V7, P251

[2] Impaired Insulin Sensitivity as Indexed by the HOMA Score Is Associated With Deficits in Verbal Fluency and Temporal Lobe Gray Matter Volume in the Elderly [J].

Benedict, Christian ;

Brooks, Samantha J. ;

Kullberg, Joel ;

Burgos, Jonathan ;

Kempton, Matthew J. ;

Nordenskjold, Richard ;

Nylander, Ruta ;

Kilander, Lena ;

Craft, Suzanne ;

Larsson, Elna-Marie ;

Johansson, Lars ;

Ahlstrom, Hakan ;

Lind, Lars ;

Schioth, Helgi B. .

DIABETES CARE, 2012, 35 (03) :488-494

[3] Brain Changes Underlying Cognitive Dysfunction in Diabetes: What Can We Learn From MRI? [J].

Biessels, Geert Jan ;

Reijmer, Yael D. .

DIABETES, 2014, 63 (07) :2244-2252

[4] An anti-diabetes agent protects the mouse brain from defective insulin signaling caused by Alzheimer's disease-associated Aβ oligomers [J].

Bomfim, Theresa R. ;

Forny-Germano, Leticia ;

Sathler, Luciana B. ;

Brito-Moreira, Jordano ;

Houzel, Jean-Christophe ;

Decker, Helena ;

Silverman, Michael A. ;

Kazi, Hala ;

Melo, Helen M. ;

McClean, Paula L. ;

Holscher, Christian ;

Arnold, Steven E. ;

Talbot, Konrad ;

Klein, William L. ;

Munoz, Douglas P. ;

Ferreira, Sergio T. ;

De Felice, Fernanda G. .

JOURNAL OF CLINICAL INVESTIGATION, 2012, 122 (04) :1339-1353

[5] PHYSIOLOGY IN INSULIN IN MAN [J].

CAHILL, GF .

DIABETES, 1971, 20 (12) :785-&

[6] Intranasal Treatment of Central Nervous System Dysfunction in Humans [J].

Chapman, Colin D. ;

Frey, William H., II ;

Craft, Suzanne ;

Danielyan, Lusine ;

Hallschmid, Manfred ;

Schithoth, Helgi B. ;

Benedict, Christian .

PHARMACEUTICAL RESEARCH, 2013, 30 (10) :2475-2484

[7] Inflammation, Defective Insulin Signaling, and Mitochondrial Dysfunction as Common Molecular Denominators Connecting Type 2 Diabetes to Alzheimer Disease [J].

De Felice, Fernanda G. ;

Ferreira, Sergio T. .

DIABETES, 2014, 63 (07) :2262-2272

[8] Alzheimer's disease and insulin resistance: translating basic science into clinical applications [J].

De Felice, Fernanda G. .

JOURNAL OF CLINICAL INVESTIGATION, 2013, 123 (02) :531-539

[9] Protection of synapses against Alzheimer's-linked toxins: Insulin signaling prevents the pathogenic binding of Aβ oligomers [J].

De Felice, Fernanda G. ;

Vieira, Marcelo N. N. ;

Bomfim, Theresa R. ;

Decker, Helena ;

Velasco, Pauline T. ;

Lambert, Mary P. ;

Viola, Kirsten L. ;

Zhao, Wei-Qin ;

Ferreira, Sergio T. ;

Klein, William L. .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (06) :1971-1976

[10] Intranasal Insulin as a Treatment for Alzheimer's Disease: A Review of Basic Research and Clinical Evidence [J].

Freiherr, Jessica ;

Hallschmid, Manfred ;

Frey, William H., II ;

Bruenner, Yvonne F. ;

Chapman, Colin D. ;

Hoelscher, Christian ;

Craft, Suzanne ;

De Felice, Fernanda G. ;

Benedict, Christian .

CNS DRUGS, 2013, 27 (07) :505-514

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