Why are we doing cardiovascular outcome trials in type 2 diabetes?

被引:1
作者
Menon, Venu [1 ]
Aggarwal, Bhuvnesh [1 ]
机构
[1] Cleveland Clin, Inst Heart & Vasc, Cleveland, OH 44195 USA
关键词
PRIMARY PREVENTION; AMERICAN-COLLEGE; GLUCOSE CONTROL; DISEASE; RISK; MORTALITY; MELLITUS; ASPIRIN; REVASCULARIZATION; CHOLESTEROL;
D O I
10.3949/ccjm.81gr.14005
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Cardiovascular disease is the leading cause of morbidity and death in people with diabetes mellitus. While worsening hyperglycemia is directly associated with poorer outcomes, studies aiming at euglycemia have failed to show an advantage over modest glucose-lowering strategies. Several diabetes drugs that were approved solely on the basis of their glucose-lowering potential were later shown to increase cardiovascular risk.
引用
收藏
页码:665 / 671
页数:7
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