Simaroubaceae family: botany, chemical composition and biological activities

被引：56
作者：
Alves, Iasmine A. B. S. [1 ]
Miranda, Henrique M. [2 ]
Soares, Luiz A. L. [1 ,2 ]
Randau, Karina P. [1 ,2 ]
机构：
[1] Univ Fed Pernambuco, Programa Posgrad Ciencias Farmaceut, Lab Farmacognosia, Recife, PE, Brazil
[2] Univ Fed Pernambuco, Dept Farm, Lab Farmacognosia, Recife, PE, Brazil
来源：
REVISTA BRASILEIRA DE FARMACOGNOSIA-BRAZILIAN JOURNAL OF PHARMACOGNOSY | 2014年 / 24卷 / 04期
关键词：
Chemical constituents; Simaba; Simarouba; Simaroubaceae; Quassia; INDONESIAN MEDICINAL-PLANTS; BETA-CARBOLINE ALKALOIDS; BRUCEA-[!text type='JAVA']JAVA[!/text]NICA FRUITS; QUASSIA-AMARA; AILANTHUS-ALTISSIMA; PICRASMA-QUASSIOIDES; BITTER PRINCIPLES; IN-VITRO; SIMALIKALACTONE-D; ANTIPLASMODIAL ACTIVITY;
D O I：
10.1016/j.bjp.2014.07.021
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The Simaroubaceae family includes 32 genera and more than 170 species of trees and brushes of pantropical distribution. The main distribution hot spots are located at tropical areas of America, extending to Africa, Madagascar and regions of Australia bathed by the Pacific. This family is characterized by the presence of quassinoids, secondary metabolites responsible of a wide spectrum of biological activities such as antitumor, antimalarial, antiviral, insecticide, feeding deterrent, amebicide, antiparasitic and herbicidal. Although the chemical and pharmacological potential of Simaroubaceae family as well as its participation in official compendia; such as British, German, French and Brazilian pharmacopoeias, and patent registration, many of its species have not been studied yet. In order to direct further investigation to approach detailed botanical, chemical and pharmacological aspects of the Simaroubaceae, the present work reviews the information regarding the main genera of the family up to 2013. (C) 2014 Sociedade Brasileira de Farmacognosia. Published by Elsevier Editora Ltda. All rights reserved.
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页码：481 / 501
页数：21
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