Neuromodulatory treatments for post-traumatic stress disorder (PTSD)

被引：49

作者：

Koek, Ralph J. ^{[1
,2
]}

Roach, Janine ^{[1
,3
]}

Athanasiou, Nicholas ^{[1
,4
]}

van't Wout-Frank, Mascha ^{[5
]}

Philip, Noah S. ^{[5
,6
]}

机构：

[1] David Geffen Sch Med Angeles, Dept Psychiat & Biobehav Sci, Los Angeles, CA USA

[2] Vet Adm Greater Los Angeles Healthcare Syst, Sepulveda Ambulatory Care Ctr, North Hills, CA USA

[3] Oliveview Med Ctr, Sylmar, CA USA

[4] San Fernando Mental Hlth Ctr, Granada Hills, CA USA

[5] Brown Univ, Dept Psychiat & Human Behav, Alpert Med Sch, Providence, RI 02912 USA

[6] Providence VA Med Ctr, VA RR&D Ctr Neurorestorat & Neurotechnol, Providence, RI USA

来源：

PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY | 2019年 / 92卷

关键词：

TRANSCRANIAL MAGNETIC STIMULATION; MAJOR DEPRESSIVE DISORDER; VAGUS NERVE-STIMULATION; CRANIAL ELECTROTHERAPY STIMULATION; EMOTION REGULATION DIFFICULTIES; VENTROMEDIAL PREFRONTAL CORTEX; FEAR EXTINCTION; BRAIN ACTIVITY; DOUBLE-BLIND; ELECTROCONVULSIVE-THERAPY;

D O I：

10.1016/j.pnpbp.2019.01.004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Electroconvulsive therapy has been used successfully in some individuals with posttraumatic stress disorder (PTSD) whose symptoms have not improved with other treatments. But there are only a few reports. Meanwhile, an array of new neuromodulation strategies, including repetitive transcranial magnetic stimulation, transcranial direct current stimulation, vagus nerve stimulation, trigeminal nerve stimulation, and deep brain stimulation have been developed and applied experimentally in the treatment of other psychiatric disorders. This article will review the clinical evidence and mechanistic basis for their use in PTSD.

引用

页码：148 / 160

页数：13

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