BASC-ing in the glow: bronchioalveolar stem cells get their place in the lung

被引：7

作者：

Basil, Maria C. ^{[1
]}

Morrisey, Edward E. ^{[1
]}

机构：

[1] Univ Penn, Penn Inst Regenerat Med, PCPB, Philadelphia, PA 19104 USA

来源：

EMBO JOURNAL | 2019年 / 38卷 / 12期

关键词：

AIRWAY; ALVEOLAR;

D O I：

10.15252/embj.2019102344

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Lung epithelial progenitor cell populations fulfill the needs of this complex facultative regenerative organ when exposed to insult and contribute to repair in either the airway or alveolar compartments. The presence of a cell that can populate both epithelia had been proposed previously but has remained elusive. In this issue, Salwig et al (2019) provide compelling, genetic evidence that supports a growing narrative-a rare population of bronchioalveolar stem cells (BASCs) that can contribute to both airway and alveolar epithelium in the distal murine lung.

引用

页数：3

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EMBO JOURNAL, 2019, 38 (12)

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