Steroidal saponins from Tribulus terrestris

被引：36

作者：

Su, Lan ^{[1
]}

Chen, Gang ^{[1
]}

Feng, Sheng-Guang ^{[1
]}

Wang, Wei ^{[2
]}

Li, Zhi-Feng ^{[1
]}

Chen, Huan ^{[1
]}

Liu, Ying-Xue ^{[1
]}

Pei, Yue-Hu ^{[1
]}

机构：

[1] Shenyang Pharmaceut Univ, Sch Tradit Chinese Mat Med, Shenyang 110016, Peoples R China

[2] Shenyang Pharmaceut Univ, Sch Life Sci & Biopharmaceut, Shenyang 110016, Peoples R China

来源：

STEROIDS | 2009年 / 74卷 / 4-5期

关键词：

Tribulus terrestris; Structural identification; Steroidal saponins; FRUITS; BULBS;

D O I：

10.1016/j.steroids.2008.12.008

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Five new steroidal saponins were isolated from the fruits of Tribulus terrestris. Their structures were fully established by spectroscopic and chemical analysis as (23S,25S)-5 alpha-spirostane-24-one-3 beta,23-diol-3-O-{alpha-L-rhamnopyranosyl-(1 -> 2)-O-[beta-D-glucopyranosyl-(1 -> 4)]-beta-D-galactopyranoside} (1), (24S,25S)-5 alpha-spirostane-3 beta,24-diol-3-O-{alpha-L-rhamnopyranosyl-(1 -> 2)-O -[beta-D-glucopyranosyl-(1 -> 4)]-beta-D-galactopyranoside} (2), 26-O-beta-D-glucopyranosuyl-(25R)-5 alpha-furostan-2 alpha,3 beta,22 alpha,26-tetraol-3-O-{beta-D-glucopyranosyl-(1 -> 2)-O-beta-D-glucopyranosyl-(1 -> 4)-beta-D-galactopyranoside} (3), 26-O-beta-D-glucopyranosyl-(25R)-5 alpha-furostan-20(22)-en-2 alpha,3 beta,26-triol-3-O-{beta-D-glucopyranosyl-(1 -> 2)-O-beta-D-glucopyranosyl-(1 -> 4)-beta-D-galactopyranoside} (4), and 26-O-beta-D-glucopyranosyl-(25S)-5 alpha-furostan-12-one-22-methoxy-3 beta,26-diol-3-O-{alpha-L-rhamnopyranosyl-(1 -> 2)-O-[beta-D-glucopyranosyl-(1 -> 4)]-beta-D-galactopyranoside} (5). The isolated compounds were evaluated forcytostatic activity against HL-60 cells. (C) 2009 Published by Elsevier Inc.

引用

页码：399 / 403

页数：5

共 12 条

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