Metastatic gastrointestinal stromal tumor with an Exon 11 c-Kit mutation responding to the tyrosine kinase inhibitor imatinib

被引：4
作者：
Cho, H
Kobayashi, O
Tsuburaya, A
Sugiyama, Y
Sairenji, M
Motohashi, H
Yoshida, T
Miyagi, Y
Imada, T
机构：
[1] Yokohama City Univ, Kanagawa Canc Ctr, Dept Gastrointestinal Surg, Yokohama, Kanagawa 232, Japan
[2] Yokohama City Univ, Kanagawa Canc Ctr, Div Pathol, Lab Mol Diagnost, Yokohama, Kanagawa 232, Japan
[3] Yokohama City Univ, Med Ctr, Gastroenterol Ctr, Yokohama, Kanagawa 232, Japan
来源：
DIGESTIVE SURGERY | 2004年 / 21卷 / 01期
关键词：
gastrointestinal stromal tumor; imatinib; C- kit mutation;
D O I：
10.1159/000076756
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
[No abstract available]
引用
收藏
页码：74 / 77
页数：4
相关论文
共 50 条
  • [11] Understanding Rechallenge and Resistance in the Tyrosine Kinase Inhibitor Era Imatinib in Gastrointestinal Stromal Tumor
    Agulnik, Mark
    Giel, Jennifer L.
    AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS, 2014, 37 (04): : 417 - 422
  • [12] Detecting Secondary C-KIT Mutations in the Peripheral Blood of Patients with Imatinib-Resistant Gastrointestinal Stromal Tumor
    Wada, Noriko
    Kurokawa, Yukinori
    Takahashi, Tsuyoshi
    Hamakawa, Takuya
    Hirota, Seiichi
    Naka, Tetsuji
    Miyazaki, Yasuhiro
    Makino, Tomoki
    Yamasaki, Makoto
    Nakajima, Kiyokazu
    Takiguchi, Shuji
    Mori, Masaki
    Doki, Yuichiro
    ONCOLOGY, 2016, 90 (02) : 112 - 117
  • [13] Rapid Relapse after Resection of a Sunitinib-resistant Gastrointestinal Stromal Tumor Harboring a Secondary Mutation in Exon 13 of the c-KIT Gene
    Kikuchi, Hrotoshi
    Miyazaki, Shinichiro
    Setoguchi, Tomohiko
    Hiramatsu, Yoshihiro
    Ohta, Manabu
    Kamiya, Kinji
    Sakaguchi, Takanori
    Konno, Hiroyuki
    ANTICANCER RESEARCH, 2012, 32 (09) : 4105 - 4109
  • [14] Analysis of mutation and expression of c-kit and PDGFR-α gene in gastrointestinal stromal tumor
    Zheng, Song
    Chen, Li-Rong
    Wang, Hai-Jun
    Chen, Shui-Zhen
    HEPATO-GASTROENTEROLOGY, 2007, 54 (80) : 2285 - 2290
  • [15] c-kit gene mutation at exon 17 or 13 is very rare in sporadic gastrointestinal stromal tumors
    Kinoshita, K
    Isozaki, K
    Hirota, S
    Nishida, T
    Chen, H
    Nakahara, M
    Nagasawa, Y
    Ohashi, A
    Shinomura, Y
    Kitamura, Y
    Matsuzawa, Y
    JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 2003, 18 (02) : 147 - 151
  • [16] Durable response with a combination of imatinib and sorafenib in KIT exon 17 mutant gastrointestinal stromal tumor
    Singeltary, Brian
    Ghose, Abhimanyu
    Sussman, Jeffrey
    Choe, Kyuran
    Olowokure, Olugbenga
    JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2014, 5 (01) : E27 - E29
  • [17] Acquired resistance to imatinib and secondary KIT exon 13 mutation in gastrointestinal stromal tumour
    Bertucci, Francois
    Goncalves, Anthony
    Monges, Genevieve
    Madroszyk, Anne
    Guiramand, Jerome
    Moutardier, Vincent
    Noguchi, Tetsuro
    Dubreuil, Patrice
    Sobol, Hagay
    ONCOLOGY REPORTS, 2006, 16 (01) : 97 - 101
  • [18] Mast cell leukemia: identification of a new c-Kit mutation, dup(501-502), and response to masitinib, a c-Kit tyrosine kinase inhibitor
    Georgin-Lavialle, Sophie
    Lhermitte, Ludovic
    Suarez, Felipe
    Yang, Ying
    Letard, Sebastien
    Hanssens, Katia
    Feger, Frederic
    Renand, Amedee
    Brouze, Chantal
    Canioni, Danielle
    Asnafi, Vahid
    Chandesris, Marie-Olivia
    Aouba, Achille
    Gineste, Paul
    Macintyre, Elizabeth
    Mansfield, Colin D.
    Moussy, Alain
    Lepelletier, Yves
    Dubreuil, Patrice
    Hermine, Olivier
    EUROPEAN JOURNAL OF HAEMATOLOGY, 2012, 89 (01) : 47 - 52
  • [19] Gastrointestinal stromal tumours and their response to treatment with the tyrosine kinase inhibitor imatinib
    Gunhild Mechtersheimer
    Gerlinde Egerer
    Manfred Hensel
    Ralf J. Rieker
    Martin Libicher
    Thomas Lehnert
    Roland Penzel
    Virchows Archiv, 2004, 444 : 108 - 118
  • [20] Gastrointestinal stromal tumours and their response to treatment with the tyrosine kinase inhibitor imatinib
    Mechtersheimer, G
    Egerer, G
    Hensel, M
    Rieker, RJ
    Libicher, M
    Lehnert, T
    Penzel, R
    VIRCHOWS ARCHIV, 2004, 444 (02) : 108 - 118
12345