Mitochondrial metabolism in TCA cycle mutant cancer cells

被引：9
作者：
Sullivan, Lucas B. [1 ]
Chandel, Navdeep S. [1 ]
机构：
[1] Northwestern Univ, Dept Med, Feinberg Sch Med, Chicago, IL 60611 USA
来源：
CELL CYCLE | 2014年 / 13卷 / 03期
关键词：
FH; reductive carboxylation; ROS; GSF; HLRCC; mitochondria cancer; fumarate; TCA; FUMARATE; HEREDITARY; CARCINOMA; PATHWAY; ROLES;
D O I：
10.4161/cc.27513
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
引用
收藏
页码：347 / 348
页数：2
相关论文
共 50 条
  • [21] Mitochondrial targeted β-lapachone induces mitochondrial dysfunction and catastrophic vacuolization in cancer cells
    Ma, Jing
    Lim, Chaemin
    Sacher, Joshua R.
    Van Houten, Bennett
    Qian, Wei
    Wipf, Peter
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2015, 25 (21) : 4828 - 4833
  • [22] NRF2 and Mitochondrial Function in Cancer and Cancer Stem Cells
    Panieri, Emiliano
    Pinho, Sonia A.
    Afonso, Goncalo J. M.
    Oliveira, Paulo J.
    Cunha-Oliveira, Teresa
    Saso, Luciano
    CELLS, 2022, 11 (15)
  • [23] Targeting Mitochondrial Metabolism in Prostate Cancer with Triterpenoids
    Mamouni, Kenza
    Kallifatidis, Georgios
    Lokeshwar, Bal L.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2021, 22 (05) : 1 - 15
  • [24] Glutamine Starvation Affects Cell Cycle, Oxidative Homeostasis and Metabolism in Colorectal Cancer Cells
    Spada, Martina
    Piras, Cristina
    Diana, Giulia
    Leoni, Vera Piera
    Frau, Daniela Virginia
    Serreli, Gabriele
    Simbula, Gabriella
    Loi, Roberto
    Noto, Antonio
    Murgia, Federica
    Caria, Paola
    Atzori, Luigi
    ANTIOXIDANTS, 2023, 12 (03)
  • [25] Mitochondrial metabolism supports resistance to IDH mutant inhibitors in acute myeloid leukemia
    Stuani, Lucille
    Sabatier, Marie
    Saland, Estelle
    Cognet, Guillaume
    Poupin, Nathalie
    Bosc, Claudie
    Castelli, Florence A.
    Gales, Lara
    Turtoi, Evgenia
    Montersino, Camille
    Farge, Thomas
    Boet, Emeline
    Broin, Nicolas
    Larrue, Clement
    Baran, Natalia
    Cisse, Madi Y.
    Conti, Marc
    Loric, Sylvain
    Kaoma, Tony
    Hucteau, Alexis
    Zavoriti, Aliki
    Sahal, Ambrine
    Mouchel, Pierre-Luc
    Gotanegre, Mathilde
    Cassan, Cedric
    Fernando, Laurent
    Wang, Feng
    Hosseini, Mohsen
    Chu-Van, Emeline
    Le Cam, Laurent
    Carroll, Martin
    Selak, Mary A.
    Vey, Norbert
    Castellano, Remy
    Fenaille, Francois
    Turtoi, Andrei
    Cazals, Guillaume
    Bories, Pierre
    Gibon, Yves
    Nicolay, Brandon
    Ronseaux, Sebastien
    Marszalek, Joseph R.
    Takahashi, Koichi
    DiNardo, Courtney D.
    Konopleva, Marina
    Pancaldi, Vera
    Collette, Yves
    Bellvert, Floriant
    Jourdan, Fabien
    Linares, Laetitia K.
    JOURNAL OF EXPERIMENTAL MEDICINE, 2021, 218 (05)
  • [26] Mitochondrial metabolism in hematopoietic stem cells requires functional FOXO3
    Rimmele, Pauline
    Liang, Raymond
    Bigarella, Carolina L.
    Kocabas, Fatih
    Xie, Jingjing
    Serasinghe, Madhavika N.
    Chipuk, Jerry
    Sadek, Hesham
    Zhang, Cheng Cheng
    Ghaffari, Saghi
    EMBO REPORTS, 2015, 16 (09) : 1164 - 1176
  • [27] Increased inflammatory lipid metabolism and anaplerotic mitochondrial activation follow acquired resistance to vemurafenib in BRAF-mutant melanoma cells
    Delgado-Goni, Teresa
    Galobart, Teresa Casals
    Wantuch, Slawomir
    Normantaite, Deimante
    Leach, Martin O.
    Whittaker, Steven R.
    Beloueche-Babari, Mounia
    BRITISH JOURNAL OF CANCER, 2020, 122 (01) : 72 - 81
  • [28] Disrupting Mitochondrial Pyruvate Uptake Directs Glutamine into the TCA Cycle away from Glutathione Synthesis and Impairs Hepatocellular Tumorigenesis
    Tompkins, Sean C.
    Sheldon, Ryan D.
    Rauckhorst, Adam J.
    Noterman, Maria F.
    Solst, Shane R.
    Buchanan, Jane L.
    Mapuskar, Kranti A.
    Pewa, Alvin D.
    Gray, Lawrence R.
    Oonthonpan, Lalita
    Sharma, Arpit
    Scerbo, Diego A.
    Dupuy, Adam J.
    Spitz, Douglas R.
    Taylor, Eric B.
    CELL REPORTS, 2019, 28 (10): : 2608 - +
  • [29] TCA cycle-powered synthesis of fucosylated oligosaccharides
    Guan, Ningzi
    Shin, Hyun-Dong
    Long, Lingfeng
    Azadi, Parastoo
    Chen, Rachel
    GLYCOBIOLOGY, 2018, 28 (07) : 468 - 473
  • [30] Acetate metabolism in cancer cells
    Aaron M Hosios
    Matthew G Vander Heiden
    Cancer & Metabolism, 2 (1)
12345