Advances and challenges in the prevention and treatment of COVID-19

被引：14
作者：
Han, Yan-Jie [1 ,2 ,3 ]
Ren, Zhi-Guang [1 ,2 ]
Li, Xin-Xin [3 ]
Yan, Ji-Liang [3 ]
Ma, Chun-Yan [3 ]
Wu, Dong-Dong [1 ,2 ,4 ]
Ji, Xin-Ying [1 ,2 ]
机构：
[1] Henan Univ, Sch Basic Med Sci, Kaifeng Key Lab Infect Dis & Biosafety, Kaifeng 475004, Henan, Peoples R China
[2] Henan Univ, Sch Basic Med Sci, Henan Int Joint Lab Nucl Prot Regulat, Kaifeng 475004, Henan, Peoples R China
[3] Kaifeng Cent Hosp, Clin Lab & Funct Lab, Kaifeng 475000, Henan, Peoples R China
[4] Henan Univ, Sch Stomatol, Kaifeng 475004, Henan, Peoples R China
来源：
INTERNATIONAL JOURNAL OF MEDICAL SCIENCES | 2020年 / 17卷 / 12期
基金：
中国国家自然科学基金;
关键词：
SARS-CoV-2; COVID-19; virological characteristics; clinical treatment; drugs; RESPIRATORY SYNDROME CORONAVIRUS; VITRO ANTIVIRAL ACTIVITY; FAVIPIRAVIR T-705; SARS-COV; MERS-COV; RIBAVIRIN; VIRUS; REPLICATION; ACE2; INHIBITORS;
D O I：
10.7150/ijms.47836
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Since the end of 2019, a new type of coronavirus pneumonia (COVID-19) caused by the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) has been spreading rapidly throughout the world. Previously, there were two outbreaks of severe coronavirus caused by different coronaviruses worldwide, namely Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) and the Middle East Respiratory Syndrome Coronavirus (MERS-CoV). This article introduced the origin, virological characteristics and epidemiological overview of SARS-CoV-2, reviewed the currently known drugs that may prevent and treat coronavirus, explained the characteristics of the new coronavirus and provided novel information for the prevention and treatment of COVID-19.
引用
收藏
页码：1803 / 1810
页数：8
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