Do alterations in inter-ictal heart rate variability predict sudden unexpected death in epilepsy?

被引：61

作者：

Surges, R. ^{[1
]}

Henneberger, C. ^{[1
]}

Adjei, P. ^{[1
]}

Scott, C. A. ^{[1
]}

Sander, J. W. ^{[1
,2
]}

Walker, M. C. ^{[1
]}

机构：

[1] UCL, Inst Neurol, Dept Clin & Expt Epilepsy, London, England

[2] Netherlands Fdn, SEIN Epilepsy Inst, Heemstede, Netherlands

来源：

EPILEPSY RESEARCH | 2009年 / 87卷 / 2-3期

基金：

英国惠康基金;

关键词：

Heart rate variability; Autonomic dysfunction; Sympathetic tone; Sudden unexpected death in epilepsy; Nocturnal seizures; TEMPORAL-LOBE EPILEPSY; AUTONOMIC CARDIAC CONTROL; RISK-FACTORS; WITHDRAWAL; SLEEP; SUDEP;

D O I：

10.1016/j.eplepsyres.2009.08.008

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Reduced heart rate variability (HRV) may predispose to sudden unexpected death in epilepsy (SUDEP). We ascertained whether HRV predicts SUDEP in chronic epilepsy using a case-control design and investigated parameters of inter-ictal HRV in 14 patients (7 had died from SUDEP). No HRV parameter was associated with SUDEP. Thus, although altered HRV might be involved in SUDEP, HRV parameters are not clear-cut predictors for SUDEP. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：277 / 280

页数：4

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