Efficient Suzuki coupling of aryl chlorides catalyzed by palladium(0) with a P,N heteroligand and isolation of unsaturated intermediates

被引：55

作者：

Weng, ZQ

Teo, SH

Koh, LL

Hor, TSA

机构：

[1] Natl Univ Singapore, Dept Chem, Singapore 117543, Singapore

[2] Inst Chem & Engn Sci, Jurong Isl 627833, Singapore

来源：

ORGANOMETALLICS | 2004年 / 23卷 / 19期

关键词：

D O I：

10.1021/om0494770

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

A mixture of Pd-2(dba)(3) / [eta-C5H4CH=N(C6H5)]-Fe[eta-C5H4P(t-Bu)(2)] (1) efficiently catalyzes the Suzuki cross-couplings of a range of arylboronic acids and aryl chlorides, affording the desired biaryl products in high isolated yields. Two catalytically active Pd(0) intermediates, viz. 16-electron [eta-C5H4CH=N(C6H5)]Fe[eta-C5H4P(t-Bu)(2)]Pd(dba) (2) and 14-electron linear Pd{[eta-C5H4CH=N(C6H5)]Fe[eta-C5H4P(t-BU)(2)]}(2) (3) together with an oxidative addition product are isolated and crystallographically established.

引用

页码：4342 / 4345

页数：4

共 36 条

[1] An N-heterocyclic carbene ligand with flexible steric bulk allows Suzuki cross-coupling of sterically hindered aryl chlorides at room temperature [J].