Effects of L-carnitine on reproductive performance, milk composition, placental development and IGF concentrations in blood plasma and placental chorions in sows

被引：8

作者：

Zhang, Shihai ^{[1
]}

Tian, Min ^{[1
]}

Song, Hanqing ^{[1
]}

Shi, Kui ^{[1
]}

Wang, Yijiang ^{[1
]}

Guan, Wutai ^{[1
]}

机构：

[1] South China Agr Univ, Guangdong Prov Key Lab Anim Nutr Control, Coll Anim Sci, Guangzhou, Guangdong, Peoples R China

来源：

ARCHIVES OF ANIMAL NUTRITION | 2018年 / 72卷 / 04期

关键词：

Carnitine; insulin-like growth factors; milk composition; placenta; reproductive performance; sows; DIETARY L-CARNITINE; GROWTH-FACTORS; FETAL-GROWTH; BINDING-PROTEIN; SUPPLEMENTATION; LACTATION; IMPROVES; PREGNANCY; SYSTEM;

D O I：

10.1080/1745039X.2018.1471185

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

Recent studies have shown that L-carnitine supplementation of sows during pregnancy and lactation enhances their reproductive performance, but the underlying mechanisms are still needed to be further confirmed. This study was conducted to investigate the function of L-carnitine on placental development, milk nutrient content and release of hormones in sows. In this experiment, 40 multiparous crossbred sows (Yorkshire x Landrace) were allotted to two groups fed diets with or without a supplemental 50mg/kg L-carnitine. The experimental diets were fed from d 1 post-coitus until d 21 post-partum. L-carnitine-treated sow had fewer weak piglets (p<0.05) and a greater percentage of oestrus by 5 after 5-d post-partum (p<0.05) than control sows. The percentage fat from colostrum was greater in L-carnitine-treated sow than control sows (p<0.05). L-carnitine-treated sows had greater plasma concentrations of triglyceride and insulin-like growth factor (IGF)-1 and lesser plasma concentrations of glucose and IGF-binding protein (IGFBP-3) on day 60 of pregnancy (p<0.05). A clearer structure of chorions, better-developed capillaries and absence of necrosis were observed in L-carnitine-treated sows compared with control sows. The protein abundance of IGF-1 and IGF-2 in placental chorions was greater in L-carnitine-treated sows compared with control sows (p<0.05). This study suggests that sows fed an L-carnitine supplemented diet during pregnancy improved reproductive performance through enhancement of placental development and by increasing IGF concentrations in blood plasma and placental chorions.

引用

页码：261 / 274

页数：14

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