Plasmonic optical sensor for determination of refractive index of human skin tissues

被引:15
作者
Sharma, Anuj K. [1 ]
Mohr, Gerhard J. [2 ]
机构
[1] Natl Inst Technol Delhi, Dept Appl Sci, A-7 Inst Area, Delhi 110040, India
[2] Joanneum Res Forsch Gesell mbH Mat, Franz Pichler Str 30, A-8160 Weiz, Austria
关键词
Refractive index; Skin tissue; Plasmon; Biosensor; Substrate; 8; WAVELENGTHS; RESONANCE; SENSITIVITY; BIOSENSOR; NM;
D O I
10.1016/j.snb.2015.11.119
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
A surface plasmon resonance (SPR) based optical sensor for the determination of refractive index of human skin tissue samples is proposed. Previous experimental results describing variation of refractive index of skin tissue samples with wavelength are considered for theoretical calculations. The angular interrogation method along with glass substrate and Au-Al bimetal layer is considered. The sensor's performance is closely analyzed in terms of well-defined performance indicators in order to achieve reliable and accurate sensing performance. The influence of operating wavelength on the performance of sensor scheme is investigated. Performance comparison for two different substrates (2S2G and SF10) is carried out. The proposed sensor has the potential to provide high sensitivity, precision, and resolution, thereby opening an easy and reliable window for dermatological applications. (C) 2015 Elsevier B.V. All rights reserved.
引用
收藏
页码:312 / 317
页数:6
相关论文
共 23 条
[1]   A SPR Aptasensor for Detection of Avian Influenza Virus H5N1 [J].
Bai, Hua ;
Wang, Ronghui ;
Hargis, Billy ;
Lu, Huaguang ;
Li, Yanbin .
SENSORS, 2012, 12 (09) :12506-12518
[2]   Linearity Indices and Linearity Improvement of 2-D Tetralateral Position-Sensitive Detector [J].
Cui, Song ;
Soh, Yeng Chai .
IEEE TRANSACTIONS ON ELECTRON DEVICES, 2010, 57 (09) :2310-2316
[3]   Refractive indices of human skin tissues at eight wavelengths and estimated dispersion relations between 300 and 1600 nm [J].
Ding, HF ;
Lu, JQ ;
Wooden, WA ;
Kragel, PJ ;
Hu, XH .
PHYSICS IN MEDICINE AND BIOLOGY, 2006, 51 (06) :1479-1489
[4]   Determination of refractive indices of porcine skin tissues and Intralipid at eight wavelengths between 325 and 1557 nm [J].
Ding, HF ;
Lu, JQ ;
Jacobs, KM ;
Hu, XH .
JOURNAL OF THE OPTICAL SOCIETY OF AMERICA A-OPTICS IMAGE SCIENCE AND VISION, 2005, 22 (06) :1151-1157
[5]  
Jenkins F.A., 1981, Fundamentals of Optics, V4th
[6]   Design of a silicon-based plasmonic biosensor chip for human blood-group identification [J].
Jha, Rajan ;
Sharma, Anuj K. .
SENSORS AND ACTUATORS B-CHEMICAL, 2010, 145 (01) :200-204
[7]   High-performance sensor based on surface plasmon resonance with chalcogenide prism and aluminum for detection in infrared [J].
Jha, Rajan ;
Sharma, Anuj K. .
OPTICS LETTERS, 2009, 34 (06) :749-751
[8]   Imaging surface plasmon resonance sensor based on multiple wavelengths:: Sensitivity considerations [J].
Johansen, K ;
Arwin, H ;
Lundström, I ;
Liedberg, B .
REVIEW OF SCIENTIFIC INSTRUMENTS, 2000, 71 (09) :3530-3538
[9]   A FIBEROPTIC CHEMICAL SENSOR-BASED ON SURFACE-PLASMON RESONANCE [J].
JORGENSON, RC ;
YEE, SS .
SENSORS AND ACTUATORS B-CHEMICAL, 1993, 12 (03) :213-220
[10]   Study of Immobilization Procedure on Silver Nanolayers and Detection of Estrone with Diverged Beam Surface Plasmon Resonance (SPR) Imaging [J].
Karabchevsky, Alina ;
Tsapovsky, Lev ;
Marks, Robert S. ;
Abdulhalim, Ibrahim .
BIOSENSORS-BASEL, 2013, 3 (01) :157-170