Background : In the past diverticulitis was believed to be uncommon in the young population. However, there is growing concern suggesting that these patients develop more severe clinical symptoms and may require more frequent intervention. Methods : We performed a retrospective chart review of patients with diverticulitis in individuals with age less than 40 years over an 8 year period (2007-2015). Diagnosis was confirmed with a CT scan. In addition to age we took into consideration race, gender, anemia (hematocrit< 41), leukocytosis (WBC > 12), BMI and whether it was an initial episode or recurrence. Our outcome variables were complications (abscess, fistula, and perforation, results of colonoscopy (polyps or colon cancer)) and whether the patient required surgery. Results : We identified 123 patients who were less than 40 years old with the diagnosis of diverticulitis. There was greater than a 3: 1 ratio of males to females (77% males and 23% females) with an average age of 32.6 year. The race of the patients was nearly entirely Hispanic (88.6%). With regards to the outcome variables, 18.7% had abscesses as a complication. Perforations were observed in 26% of the patients, of which one was complicated by a fistula. A total of 25 (20%) patients went to surgery. Of these, 21 had an abscess, perforation, or tubular adenomatous polyps (TAP). Follow-up colonoscopy post-diverticulitis results were available for 42 patients. Of those patients, 9 had hyperplastic polyps and 3 had TAP. The remaining 30 patients had no polyps. No colon cancer or villous polyps were found in the entire cohort. Conclusion : Our study highlights that young patients who have an index case of uncomplicated diverticulitis with no other risk factors or complications may not gain further benefit from routine colonoscopy as once traditionally thought.
机构:
Department of Surgery, Surgical Outcomes Research Center UW Medical Center, University of WashingtonDepartment of Surgery, Surgical Outcomes Research Center UW Medical Center, University of Washington
Vlad V Simianu
David R Flum
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Department of Surgery, Surgical Outcomes Research Center UW Medical Center, University of WashingtonDepartment of Surgery, Surgical Outcomes Research Center UW Medical Center, University of Washington
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Mayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USAMayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA
Lee, Tae Hee
Setty, Pratyusha Tirumani
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Mayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USAMayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA
Setty, Pratyusha Tirumani
Parthasarathy, Gopanandan
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Mayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USAMayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA
Parthasarathy, Gopanandan
Bailey, Kent R.
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Mayo Clin, Dept Hlth Sci Res, Rochester, MN USAMayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA
Bailey, Kent R.
Wood-Wentz, Christina M.
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Mayo Clin, Dept Hlth Sci Res, Rochester, MN USAMayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA
Wood-Wentz, Christina M.
Fletcher, Joel G.
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Mayo Clin, Dept Radiol, Rochester, MN USAMayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA
Fletcher, Joel G.
Takahashi, Naoki
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Mayo Clin, Dept Radiol, Rochester, MN USAMayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA
Takahashi, Naoki
Khosla, Sundeep
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Mayo Clin, Div Endocrinol Diabet Metab & Nutr, Rochester, MN USA
Mayo Clin, Dept Physiol & Biomed Engn, Rochester, MN USAMayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA
Khosla, Sundeep
Moynagh, Michael R.
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Mayo Clin, Dept Radiol, Rochester, MN USAMayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA
Moynagh, Michael R.
Zinsmeister, Alan R.
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Mayo Clin, Dept Hlth Sci Res, Rochester, MN USAMayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA
Zinsmeister, Alan R.
Bharucha, Adil E.
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Mayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USAMayo Clin, Div Gastroenterol & Hepatol, 200 First St SW, Rochester, MN 55905 USA
机构:
VA Bedford Healthcare Syst, Bedford, MA 01730 USA
Univ Minnesota, Minneapolis, MN USAVA Bedford Healthcare Syst, Bedford, MA 01730 USA
Harris, J. Irene
Hanson, Devin
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Hennepin Healthcare, Minneapolis, MN USAVA Bedford Healthcare Syst, Bedford, MA 01730 USA
Hanson, Devin
Leskela, Jennie
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Univ Minnesota, Minneapolis, MN USA
ABPP Minneapolis VA Hlth Care Syst, Minneapolis, MN USAVA Bedford Healthcare Syst, Bedford, MA 01730 USA
Leskela, Jennie
Billig, John
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Vet Hlth Adm, Natl Ctr Eth Hlth Care, ABPP, Washington, DC USAVA Bedford Healthcare Syst, Bedford, MA 01730 USA
Billig, John
Padilla-Martinez, Viviana
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Bay Pines VA Hlth Care Syst, Bay Pines, FL USAVA Bedford Healthcare Syst, Bedford, MA 01730 USA
Padilla-Martinez, Viviana
Boyd, Jennifer
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San Francisco VA Hlth Care Syst, San Francisco, CA USA
Univ Calif San Francisco, San Francisco, CA 94143 USAVA Bedford Healthcare Syst, Bedford, MA 01730 USA
Boyd, Jennifer
Nienow, Tasha
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Minneapolis VA Hlth Care Syst, Minneapolis, MN USAVA Bedford Healthcare Syst, Bedford, MA 01730 USA