Random transverse motion-induced spatial compounding for fiber bundle imaging

被引:26
作者
Cheon, Gyeong Woo [1 ]
Cha, Jaepyeong [1 ]
Kang, Jin U. [1 ]
机构
[1] Johns Hopkins Univ, Dept Elect & Comp Engn, Baltimore, MD 21218 USA
关键词
MICROSCOPY; IMAGES; TISSUE;
D O I
10.1364/OL.39.004368
中图分类号
O43 [光学];
学科分类号
070207 ; 0803 ;
摘要
We propose and demonstrate a novel fiber bundle imaging based on spatial compounding induced by random transverse motion to remove the pixelation effect, to improve resolution, and to increase image quality. The experimental results using a USAF target and pyramidal neuron cell showed that 20-frame compounding improved image quality (contrast-to-noise ratio by >9 dB, global SNR by >6 dB, equivalent number of looks by >1.8 times, and 1/beta by >1.5 times), resolution by better than 2 mu m, and completely eliminated pixelation artifact. (C) 2014 Optical Society of America
引用
收藏
页码:4368 / 4371
页数:4
相关论文
共 18 条
[1]   Speckle reduction in optical coherence tomography images by use of a spatially adaptive wavelet filter [J].
Adler, DC ;
Ko, TH ;
Fujimoto, JG .
OPTICS LETTERS, 2004, 29 (24) :2878-2880
[2]   Snapshot spectrally encoded fluorescence imaging through a fiber bundle [J].
Bedard, Noah ;
Tkaczyk, Tomasz S. .
JOURNAL OF BIOMEDICAL OPTICS, 2012, 17 (08)
[3]   Template matching using fast normalized cross correlation [J].
Briechle, K ;
Hanebeck, UD .
OPTICAL PATTERN RECOGNITION XII, 2001, 4387 :95-102
[4]   Optical Imaging With the Use of a Scattering Lens [J].
Choi, Youngwoon ;
Yoon, Changhyeong ;
Kim, Moonseok ;
Choi, Wonjun ;
Choi, Wonshik .
IEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS, 2014, 20 (02)
[5]   High-speed, miniaturized fluorescence microscopy in freely moving mice [J].
Flusberg, Benjamin A. ;
Nimmerjahn, Axel ;
Cocker, Eric D. ;
Mukamel, Eran A. ;
Barretto, Robert P. J. ;
Ko, Tony H. ;
Burns, Laurie D. ;
Jung, Juergen C. ;
Schnitzer, Mark J. .
NATURE METHODS, 2008, 5 (11) :935-938
[6]  
Gmitro AF, 2009, OPT PHOTONICS NEWS, V20, P28, DOI 10.1364/OPN.20.11.000028
[7]   Robot-assisted three-dimensional registration for cochlear implant surgery using a common-path swept-source optical coherence tomography probe [J].
Gurbani, Saumya S. ;
Wilkening, Paul ;
Zhao, Mingtao ;
Gonenc, Berk ;
Cheon, Gyeong Woo ;
Iordachita, Iulian I. ;
Chien, Wade ;
Taylor, Russell H. ;
Niparko, John K. ;
Kang, Jin U. .
JOURNAL OF BIOMEDICAL OPTICS, 2014, 19 (05)
[8]   Effect of multimodal coupling in imaging micro-endoscopic fiber bundle on optical coherence tomography [J].
Han, J. -H. ;
Kang, J. U. .
APPLIED PHYSICS B-LASERS AND OPTICS, 2012, 106 (03) :635-643
[9]   Pixelation effect removal from fiber bundle probe based optical coherence tomography imaging [J].
Han, Jae-Ho ;
Lee, Junghoon ;
Kang, Jin U. .
OPTICS EXPRESS, 2010, 18 (07) :7427-7439
[10]   Improving spatial resolution of a fiber bundle optical biopsy system [J].
Kyrish, Matthew ;
Kester, Robert ;
Richards-Kortum, Rebecca ;
Tkaczyk, Tomasz .
ENDOSCOPIC MICROSCOPY V, 2010, 7558