RTGAN: ORGAN CONTOURS IN RADIATION THERAPY WITH GENERATIVE ADVERSARIAL NETWORK

被引:0
作者
Chin, Chiun-Li [1 ]
Tseng, Hsien-Chun [2 ,5 ]
Shao, Yu-Hsiang [3 ]
Hsu, Chin-Luen [4 ]
Lin, Hsin-Yu [5 ]
Chang, Hsi-Chang [5 ]
Hsieh, Ya-Ju [3 ]
机构
[1] Chung Shan Med Univ, Dept Med Informat, Taichung, Taiwan
[2] Chung Shan Med Univ, Sch Med, Taichung, Taiwan
[3] Natl Taiwan Univ, Grad Inst Biomed Elect & Bioinformat, Taipei, Taiwan
[4] Natl Chiao Tung Univ, Inst Bioinformat & Syst Biol, Hsinchu, Taiwan
[5] Chung Shan Med Univ Hosp, Dept Radiat Oncol, Taichung, Taiwan
来源
BIOMEDICAL ENGINEERING-APPLICATIONS BASIS COMMUNICATIONS | 2021年 / 33卷 / 02期
关键词
RTGAN; GAN; Radiation therapy; Organ contouring; Deep learning; SEGMENTATION; ATLAS; MRI; RADIOTHERAPY; HEAD;
D O I
10.4015/S1016237221500149
中图分类号
R318 [生物医学工程];
学科分类号
0831 ;
摘要
Generally, radiation oncology applies evaluation and prediction in medical imaging and diagnosis, specifically for contouring organs, which results in the production of the clinical target volume (CTV) that corresponds to disease risk and organ exclusion. Medical physicists contour organs and combine computed tomography (Cl') scans to digital imaging and communications in medicine (DiCOM) radiation therapy (RT) to assist physicians for diagnosing tumors and calculating the dosages in treatments including radiation and chemotherapy. Thus, to generate RT images with high accuracy, this paper proposes a new Generator Adversarial Network (GAN) for RT images called radiation therapy GAN (RTGAN). We combine multiple loss functions with synthetic similarity DICOM-RT images and compare the results with Pinnacle, a radiation oncology treatment planning system. Further, we evaluate the method to get a score of 0.984 in structured similarity (SSIM) and 31.26 in peak signal-to-noise ratio (PSNR) and find that it costs 0.058 s to finish contouring one CT image. The proposed method is applied and tested in the department of radiation oncology at the Chung Shan Medical University Hospital, and the results are similar to the ground truth images. Thus, it not. only effectively reduces the false-positive rate but also makes a breakthrough in medicine.
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页数:12
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