Efficient synthesis of aliphatic sulfones by Mg mediated coupling reactions of sulfonyl chlorides and aliphatic halides

被引：24

作者：

Fu, Ying ^{[1
]}

Xu, Qin-Shan ^{[1
]}

Li, Quan-Zhou ^{[1
]}

Du, Zhengyin ^{[1
]}

Wang, Ke-Hu ^{[1
]}

Huang, Danfeng ^{[1
]}

Hu, Yulai ^{[1
]}

机构：

[1] Northwest Normal Univ, Coll Chem & Chem Engn, Minist Educ, Key Lab Ecoenvironm Related Polymer Mat, Lanzhou 730070, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2017年 / 15卷 / 13期

基金：

中国国家自然科学基金;

关键词：

UNSYMMETRICAL DIARYL SULFONES; BETA-HYDROXY SULFONES; C-H SULFONYLATION; ARYLSULFONYL CHLORIDES; AQUEOUS-MEDIA; ALKYL-HALIDES; ORGANOZINC REAGENTS; ARYL HALIDES; SULFONAMIDES; DERIVATIVES;

D O I：

10.1039/c7ob00251c

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Sulfonyl chlorides were reduced to anhydrous sulfinate salts with magnesium under sonication. These sulfinates were alkylated to sulfones with alkyl chlorides in the presence of catalytic sodium iodide under sonication. A variety of aliphatic sulfones was efficiently prepared by this one-pot two-step procedure.

引用

收藏

页码：2841 / 2845

页数：5

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