Hepatitis B infection among health workers in Uganda: Evidence of the need for health worker protection

被引:35
作者
Braka, Fiona [1 ]
Nanyunja, Miriam
Makumbi, Issa
Mbabazi, William
Kasasa, Simon
Lewis, Rosamund F.
机构
[1] WHO, Cty Off, Kampala, Uganda
[2] Makerere Univ, Inst Publ Hlth, Dept Epidemiol & Biostat, Kampala, Uganda
[3] Minist Hlth, Uganda Natl Expanded Programme Immunisat, Kampala, Uganda
关键词
hepatitis B; health workers; vaccination; Uganda;
D O I
10.1016/j.vaccine.2006.08.029
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Hepatitis B exposure was assessed in 311 health workers in Uganda, a highly endemic country. Health workers were selected by random sampling from a categorized list of health workers at district level, proportionate to the population of each district. Whereas 60.1% of health workers have evidence of hepatitis B infection, with 8.7% being chronic carriers and one (0.3%) acutely infected, 36.3% are still susceptible and could benefit from vaccination. Only 5.1% reported having had at least one dose of hepatitis B vaccine and 3.5% were apparently immune through vaccination. Needle stick injuries reported by 77% of health workers were the most common mode of exposure to blood and body fluids. Trends suggested duration of service as a predictor while age and history of blood transfusion remained significant independent risk factors for hepatitis B infection. 98% of health workers are willing to be vaccinated. These results confirm the need for protection and vaccination of health workers in Uganda against hepatitis B. (c) 2006 Elsevier Ltd. All rights reserved.
引用
收藏
页码:6930 / 6937
页数:8
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