Analysis of gene expression profile during 3T3-L1 preadipocyte differentiation

被引：101
|
作者：
Guo, XM
Liao, K [1 ]
机构：
[1] Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Life Sci Res Ctr, Shanghai 200031, Peoples R China
[2] Chinese Acad Sci, Shanghai Inst Biol Sci, Shanghai Inst Biochem, Shanghai 200031, Peoples R China
来源：
GENE | 2000年 / 251卷 / 01期
关键词：
3T3-L1; adipocyte; adipogenesis; adipocyte specific genes; cDNA/EST microarray;
D O I：
10.1016/S0378-1119(00)00192-X
中图分类号：
Q3 [遗传学];
学科分类号：
071007 ; 090102 ;
摘要：
Cellular differentiation is a process in which a group of differentiation specific genes is programmatically induced. This gene expression program leads to changes in both cellular morphological and physiological phenotypes. Using an 18,376-member cDNA/EST microarray, we analyzed the difference in gene expression profiles between differentiated 3T3-L1 adipocyte and nondifferentiated 3T3-L1 preadipocyte. From our study a large number of genes and ESTs were identified as differentially induced or suppressed. In this paper we describe the changes of gene expression profile during 3T3-L1 cell differentiation. (C) 2000 Elsevier Science B.V. All rights reserved.
引用
收藏
页码：45 / 53
页数：9
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