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- [31] Discovery of ((S)-5-(Methoxymethyl)-7-(1-methyl-1H-indol-2-yl)-2-(trifluoromethyl)-4,7-dihydropyrazolo[1,5-a]pyrimidin-6-yl)((S)-2-(3-methylisoxazol-5-yl)pyrrolidin-1-yl)methanone As a Potent and Selective IKur Inhibitor (vol 55, pg 3036, 2012)JOURNAL OF MEDICINAL CHEMISTRY, 2013, 56 (17) : 7133 - 7133Finlay, Heather J.论文数: 0 引用数: 0 h-index: 0Lloyd, John论文数: 0 引用数: 0 h-index: 0Vaccaro, Wayne论文数: 0 引用数: 0 h-index: 0Kover, Alexander论文数: 0 引用数: 0 h-index: 0Yan, Lin论文数: 0 引用数: 0 h-index: 0Bhave, Gauri论文数: 0 引用数: 0 h-index: 0Prol, Joseph论文数: 0 引用数: 0 h-index: 0Tram Huynh论文数: 0 引用数: 0 h-index: 0Bhandaru, Rao论文数: 0 引用数: 0 h-index: 0Caringal, Yolanda论文数: 0 引用数: 0 h-index: 0DiMarco, John论文数: 0 引用数: 0 h-index: 0Gan, Jinping论文数: 0 引用数: 0 h-index: 0Harper, Tim论文数: 0 引用数: 0 h-index: 0Huang, Christine论文数: 0 引用数: 0 h-index: 0Conder, Mary Lee论文数: 0 引用数: 0 h-index: 0Sun, Huabin论文数: 0 引用数: 0 h-index: 0Levesque, Paul论文数: 0 引用数: 0 h-index: 0Blanar, Michael论文数: 0 引用数: 0 h-index: 0Atwal, Karnail论文数: 0 引用数: 0 h-index: 0Wexler, Ruth论文数: 0 引用数: 0 h-index: 0
- [32] Discovery of (2S)-8[(3R)-3-Methylmorpholin-4-yl]-1-(3-methyl-2-oxobutyl)-2-(trifluoromethyl)-3,4-dihydro-2H-pyrimido[1,2-a]pyrimidin-6-one: A Novel Potent and Selective Inhibitor of Vps34 for the Treatment of Solid TumorsJOURNAL OF MEDICINAL CHEMISTRY, 2015, 58 (01) : 376 - 400Pasquier, Benoit论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceEl-Ahmad, Youssef论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceFiloche-Romme, Bruno论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceDureuil, Christine论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceFassy, Florence论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceAbecassis, Pierre-Yves论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Drug Disposit & Safety, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceMathieu, Magali论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Struct Design Informat & Struct Biol, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceBertrand, Thomas论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Struct Design Informat & Struct Biol, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceBenard, Tsiala论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Pharmaceut Sci Operat, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceBarriere, Cedric论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, 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Vitry Sur Seine, FrancePilorge, Fabienne论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceBertin, Luc论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceRichepin, Patrick论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceArigon, Jerome论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Lead Generat Candidate Realizat LGCR C&BD, F-34184 Montpellier, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceLabrosse, Jean-Robert论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Lead Generat Candidate Realizat LGCR C&BD, F-34184 Montpellier, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceClement, Jacques论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Lead Generat Candidate Realizat LGCR C&BD, F-34184 Montpellier, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceDurand, Florence论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Lead Generat Candidate Realizat LGCR C&BD, F-34184 Montpellier, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceCombet, Romain论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Lead Generat Candidate Realizat LGCR C&BD, F-34184 Montpellier, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FrancePerraut, Pierre论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Lead Generat Candidate Realizat LGCR C&BD, F-34184 Montpellier, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceLeroy, Vincent论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceGay, Frederic论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceLefrancois, Dominique论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceBretin, Francois论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceMarquette, Jean-Pierre论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Struct Design Informat & Struct Biol, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceMichot, Nadine论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Prot Prod, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceCaron, Anne论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Global Biotherapeut, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceCastell, Christelle论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceSchio, Laurent论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceMcCort, Gary论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceGoulaouic, Helene论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceGarcia-Echeverria, Carlos论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, FranceRonan, Baptiste论文数: 0 引用数: 0 h-index: 0机构: Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France Sanofi, Oncol Drug Discovery, F-94403 Vitry Sur Seine, France
- [33] Discovery of 2-(2-chloro-6-fluorophenyl)amino)-N-(3-fluoro-5-(trifluoromethyl)phenyl)-1-methyl-7,8-dihydro-1H-[1,4]dioxino [2′,3′:3,4]benzo[1,2-d]imidazole-5-carboxamide as potent, selective and efficacious microsomal prostaglandin E2 synthase-1 (mPGES-1) inhibitorBIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2016, 26 (24) : 5977 - 5984Muthukaman, Nagarajan论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaDeshmukh, Sanjay论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaSarode, Neelam论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaTondlekar, Shital论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaTambe, Macchindra论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaPisal, Dnyandeo论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaShaikh, Mahamadhanif论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaKattige, Vidya G.论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Biol Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaHonnegowda, Srinivasa论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Biol Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaKarande, Vikas论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Biol Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaKulkarni, Abhay论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Biol Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaJadhav, Satyawan B.论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Drug Metab & Pharmacokinet, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaMahat, Mahamad Yunnus A.论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Drug Metab & Pharmacokinet, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaGudi, Girish S.论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Drug Metab & Pharmacokinet, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaKhairatkar-Joshi, Neelima论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Biol Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, IndiaGharat, Laxmikant A.论文数: 0 引用数: 0 h-index: 0机构: Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, India Glenmark Pharmaceut Ltd, Glenmark Res Ctr, Chem Res, Navi Mumbai 400709, Maharashtra, India
- [34] (+)-4-[2-[4-(8-chloro-3,10-dibromo-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]-pyridin-11(R)-yl)-1-piperidinyl]-2-oxo-ethyl]-1-piperidinecarboxamide (SCH-66336):: A very potent farnesyl protein transferase inhibitor as a novel antitumor agentJOURNAL OF MEDICINAL CHEMISTRY, 1998, 41 (24) : 4890 - 4902Njoroge, FG论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USATaveras, AG论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAKelly, J论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USARemiszewski, S论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAMallams, AK论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAWolin, R论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAAfonso, A论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USACooper, AB论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USARane, DF论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USALiu, YT论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAWong, J论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAVibulbhan, B论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAPinto, P论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USADeskus, J论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAAlvarez, CS论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAdel Rosario, J论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAConnolly, M论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAWang, J论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USADesai, J论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USARossman, RR论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USABishop, WR论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAPatton, R论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAWang, L论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAKirschmeier, P论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USABryant, MS论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USANomeir, AA论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USALin, CC论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USALiu, M论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAMcPhail, AT论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USADoll, RJ论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAGirijavallabhan, VM论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USAGanguly, AK论文数: 0 引用数: 0 h-index: 0机构: Schering Plough Corp, Res Inst, Dept Chem, Kenilworth, NJ 07033 USA
- [35] 5-Chlorothiophene-2-carboxylic Acid [(S)-2-[2-Methyl-3-(2-oxopyrrolidin-1-yl)benzenesulfonylamino]-3-(4-methylpiperazin-1-yl)-3-oxopropyl]amide (SAR107375), a Selective and Potent Orally Active Dual Thrombin and Factor Xa InhibitorJOURNAL OF MEDICINAL CHEMISTRY, 2013, 56 (23) : 9441 - 9456Meneyrol, Jerome论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-31036 Toulouse, France Sanofi Aventis R&D, F-31036 Toulouse, FranceFollmann, Markus论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, D-65926 Frankfurt, Germany Sanofi Aventis R&D, F-31036 Toulouse, FranceLassalle, Gilbert论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-31036 Toulouse, France Sanofi Aventis R&D, F-31036 Toulouse, FranceWehner, Volkmar论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, D-65926 Frankfurt, Germany Sanofi Aventis R&D, F-31036 Toulouse, FranceBarre, Guillaume论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-31036 Toulouse, France Sanofi Aventis R&D, F-31036 Toulouse, FranceRousseaux, Tristan论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-31036 Toulouse, France Sanofi Aventis R&D, F-31036 Toulouse, FranceAltenburger, Jean-Michel论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-91385 Chilly Mazarin, France Sanofi Aventis R&D, F-31036 Toulouse, FrancePetit, Frederic论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-91385 Chilly Mazarin, France Sanofi Aventis R&D, F-31036 Toulouse, FranceBocskei, Zsolt论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-67080 Strasbourg, France Sanofi Aventis R&D, F-31036 Toulouse, FranceSchreuder, Herman论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, D-65926 Frankfurt, Germany Sanofi Aventis R&D, F-31036 Toulouse, FranceAlet, Nathalie论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-31036 Toulouse, France Sanofi Aventis R&D, F-31036 Toulouse, FranceHerault, Jean-Pascal论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-31036 Toulouse, France Sanofi Aventis R&D, F-31036 Toulouse, FranceMillet, Laurence论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-31036 Toulouse, France Sanofi Aventis R&D, F-31036 Toulouse, FranceDol, Frederique论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-31036 Toulouse, France Sanofi Aventis R&D, F-31036 Toulouse, FranceFlorian, Peter论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, D-65926 Frankfurt, Germany Sanofi Aventis R&D, F-31036 Toulouse, FranceSchaeffer, Paul论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-31036 Toulouse, France Sanofi Aventis R&D, F-31036 Toulouse, FranceSadoun, Freddy论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-34184 Montpellier 04, France Sanofi Aventis R&D, F-31036 Toulouse, FranceKlieber, Sylvie论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-34184 Montpellier 04, France Sanofi Aventis R&D, F-31036 Toulouse, FranceBriot, Christophe论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-34184 Montpellier 04, France Sanofi Aventis R&D, F-31036 Toulouse, FranceBono, Francoise论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-31036 Toulouse, France Sanofi Aventis R&D, F-31036 Toulouse, FranceHerbert, Jean-Marc论文数: 0 引用数: 0 h-index: 0机构: Sanofi Aventis R&D, F-31036 Toulouse, France Sanofi Aventis R&D, F-31036 Toulouse, France
- [36] Novel tetrahydropyran analogs as dipeptidyl peptidase IV inhibitors: Profile of clinical candidate (2R,3S,5R)-2-(2,5-difluorophenyl)-5-(4,6-dihydropyrrolo[3,4-c]pyrazol-5-(1H)-yl) tetrahydro-2H-pyran-3-amine (23) (vol 23, pg 5361, 2013)BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2014, 24 (11) : 2590 - 2590Biftu, Tesfaye论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAQian, Xiaoxia论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAChen, Ping论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAFeng, Dennis论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAScapin, Giovanna论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAGao, Ying-Duo论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USACox, Jason论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USARoy, Ranabir Sinha论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAEiermann, George论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAHe, Huabing论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, PPDM Bioanalyt, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USALyons, Kathy论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, PPDM Bioanalyt, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USASalituro, Gino论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, PPDM Bioanalyt, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAPatel, Sangita论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAPetrov, Alexander论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAXu, Feng论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAXu, Shiyao Sherrie论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, PPDM Bioanalyt, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAZhang, Bei论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USACaldwell, Charles论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAWu, Joseph K.论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USALyons, Kathy论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, PPDM Bioanalyt, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USAWeber, Ann E.论文数: 0 引用数: 0 h-index: 0机构: Merck Res Labs, Rahway, NJ 07065 USA Merck Res Labs, Rahway, NJ 07065 USA
- [37] 2-aminothiazole as a novel kinase inhibitor template.: Structure-activity relationship studies toward the discovery of N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)-1-piperazinyl)]-2-methyl-4-pyrimidinyl]amino)]-1,3-thiazole-5-carboxamide (Dasatinib, BMS-354825) as a potent pan-Src kinase inhibitorJOURNAL OF MEDICINAL CHEMISTRY, 2006, 49 (23) : 6819 - 6832Das, Jagabandhu论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAChen, Ping论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USANorris, Derek论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAPadmanabha, Ramesh论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USALin, James论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAMoquin, Robert V.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAShen, Zhongqi论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USACook, Lynda S.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USADoweyko, Arthur M.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAPitt, Sidney论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAPang, Suhong论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAShen, Ding Ren论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAFang, Qiong论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAde Fex, Henry F.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAMcIntyre, Kim W.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAShuster, David J.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAGillooly, Kathleen M.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USABehnia, Kamelia论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USASchieven, Gary L.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USAWityak, John论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USABarrish, Joel C.论文数: 0 引用数: 0 h-index: 0机构: Bristol Myers Squibb Pharmaceut Res Inst, Princeton, NJ 08543 USA
- [38] Synthesis and Pharmacological Characterization of C4-(Thiotriazolyl)-substituted-2-aminobicyclo[3.1.0]hexane-2,6-dicarboxylates. 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