Is variation in the gene encoding insulin-degrading enzyme (IDE) a risk factor in late-onset Alzheimer's disease?

被引:0
|
作者
Nowotny, P
Smemo, S
Hinrichs, T
Holmans, P
Tracey, K
Doil, L
Grupe, A
Goate, A
机构
[1] Washington Univ, Sch Med, St Louis, MO 63130 USA
[2] Univ Wales Coll Cardiff, Coll Med, Cardiff CF1 3NS, S Glam, Wales
[3] Celera Diagnost, Alameda, CA USA
关键词
D O I
10.1016/S0197-4580(04)81637-3
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
引用
收藏
页码:S496 / S497
页数:2
相关论文
共 50 条
  • [21] Genetic association studies of insulin-degrading enzyme (IDE) with late onset Alzheimer's disease (LOAD) - Equivocal results from two large case-control studies
    Lau, KF
    Rowland, C
    Tacey, K
    Doil, L
    Li, YH
    van Luchene, R
    Nowotny, O
    Smemo, S
    Garcia, V
    Lovestone, S
    Owen, M
    Williams, J
    Grupe, A
    Goate, A
    NEUROBIOLOGY OF AGING, 2004, 25 : S493 - S493
  • [22] Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes
    Natalia Rudovich
    Olga Pivovarova
    Eva Fisher
    Antje Fischer-Rosinsky
    Joachim Spranger
    Matthias Möhlig
    Matthias B. Schulze
    Heiner Boeing
    Andreas F. H. Pfeiffer
    Journal of Molecular Medicine, 2009, 87 : 1145 - 1151
  • [23] Polymorphisms within insulin-degrading enzyme (IDE) gene determine insulin metabolism and risk of type 2 diabetes
    Rudovich, Natalia
    Pivovarova, Olga
    Fisher, Eva
    Fischer-Rosinsky, Antje
    Spranger, Joachim
    Moehlig, Matthias
    Schulze, Matthias B.
    Boeing, Heiner
    Pfeiffer, Andreas F. H.
    JOURNAL OF MOLECULAR MEDICINE-JMM, 2009, 87 (11): : 1145 - 1151
  • [25] Insulin-degrading enzyme is genetically associated with Alzheimer's disease in the Finnish population
    Vepsalainen, Saila
    Parkinson, Michele
    Helisalmi, Seppo
    Mannermaa, Arto
    Soininen, Hilkka
    Tanzi, Rudolph E.
    Bertram, Lars
    Hiltunen, Mikko
    JOURNAL OF MEDICAL GENETICS, 2007, 44 (09) : 606 - 608
  • [26] A polymorphism in the cystatin C gene is a novel risk factor for late-onset Alzheimer's disease
    Crawford, FC
    Freeman, MJ
    Schinka, JA
    Abdullah, LI
    Gold, M
    Hartman, R
    Krivian, K
    Morris, MD
    Richards, D
    Duara, R
    Anand, R
    Mullan, MJ
    NEUROLOGY, 2000, 55 (06) : 763 - 768
  • [27] Insulin-degrading enzyme: new therapeutic target for diabetes and Alzheimer's disease?
    Pivovarova, Olga
    Hoehn, Annika
    Grune, Tilman
    Pfeiffer, Andreas F. H.
    Rudovich, Natalia
    ANNALS OF MEDICINE, 2016, 48 (08) : 614 - 624
  • [28] Characteristics of Insulin-degrading Enzyme in Alzheimer's Disease: A Meta-analysis
    Zhang, Huifeng
    Liu, Dan
    Huang, Huanhuan
    Zhao, Yujia
    Zhou, Hui
    CURRENT ALZHEIMER RESEARCH, 2018, 15 (07) : 610 - 617
  • [29] Association study between insulin-degrading enzyme gene polymorphisms and Alzheimer's disease in Japanese population
    Sakai, A
    Ujike, H
    Nakatab, K
    Ishihara, T
    Terada, S
    Kuroda, S
    Imamura, T
    Yamamoto, M
    Fujisawa, Y
    Takehisa, Y
    Kanzaki, A
    NEUROBIOLOGY OF AGING, 2002, 23 (01) : S341 - S341
  • [30] Reduced hippocampal insulin degrading enzyme in late-onset Alzheimer's disease is associated with the apolipoprotein E-ε4 allele
    McMillan, P
    Cook, D
    Leverenz, J
    Kulstad, J
    Schellenberg, G
    Craft, S
    Ericksen, S
    Jin, LW
    Roth, R
    Kovacina, K
    NEUROBIOLOGY OF AGING, 2002, 23 (01) : S400 - S400