Polyarylated Thiazoles via a Combined Halogen Dance - Cross-Coupling Strategy

被引：17
作者：
Schnuerch, Michael [1 ]
Khan, Ather Farooq [1 ]
Mihovilovic, Marko D. [1 ]
Stanetty, Peter [1 ]
机构：
[1] Vienna Univ Technol, Inst Appl Synthet Chem, A-1060 Vienna, Austria
来源：
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY | 2009年 / 2009卷 / 19期
关键词：
Protein kinase inhibitor analogues; Halogen dance; Cross-coupling; Palladium; Polyarylated thiazoles; HALOPYRIDINYLBORONIC ACIDS; BIOLOGICAL EVALUATION; EFFICIENT ACCESS; IMIDAZOLE; OXAZOLE; ESTERS;
D O I：
10.1002/ejoc.200900092
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The application of the halogen dance reaction for the synthesis of starting materials for cross-coupling reactions is reported. The obtained compounds were then successfully applied in sequential Stille and Suzuki-Miyaura cross-coupling reactions to obtain novel thiazole derivatives. ((C) Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)
引用
收藏
页码：3228 / 3236
页数：9
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