Hepatitis C virus transmission by a blood donation negative in nucleic acid amplification tests for viral RNA

被引：99

作者：

Schüttler, CG ^{[1
]}

Caspari, G ^{[1
]}

Jursch, CA ^{[1
]}

Willems, WR ^{[1
]}

Gerlich, WH ^{[1
]}

Schaefer, S ^{[1
]}

机构：

[1] Univ Giessen, Inst Med Virol, D-35392 Giessen, Germany

来源：

LANCET | 2000年 / 355卷 / 9197期

关键词：

D O I：

10.1016/S0140-6736(99)04719-4

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hepatitis C virus (HCV) was transmitted by transfusion of a platelet concentrate made from an anti-HCV and HCV-PCR-negative blood donation. Even a negative nucleic acid amplification test cannot completely prevent transmission of HCV.

引用

页码：41 / 42

页数：2

共 5 条

[1] Comparison of the rate of sequence variation in the hypervariable region of E2/NS1 region of hepatitis C virus in normal and hypogammaglobulinemic patients [J].

Booth, JCL ;

Kumar, U ;

Webster, D ;

Monjardino, J ;

Thomas, HC .

HEPATOLOGY, 1998, 27 (01) :223-227

[2] International collaborative study on the second EUROHEP HCV-RNA reference panel [J].

Damen, M ;

Cuypers, HTM ;

Zaaijer, HL ;

Reesink, HW ;

Schaasberg, WP ;

Gerlich, WH ;

Niesters, HGM ;

Lelie, PN .

JOURNAL OF VIROLOGICAL METHODS, 1996, 58 (1-2) :175-185

[3]

Glück D, 1998, INFUSIONSTHERAPIE, V25, P82

[4]

OHNO O, 1997, J CLIN MICROBIOL, V35, P201

[5] The risk of transfusion-transmitted viral infections [J].

Schreiber, GB ;

Busch, MP ;

Kleinman, SH ;

Korelitz, JJ .

NEW ENGLAND JOURNAL OF MEDICINE, 1996, 334 (26) :1685-1690

← 1 →