A fluidic MEMS for protein identification by electrospray ionization/mass spectrometry

被引：0

作者：

Druon, C ^{[1
]}

Mélique, X ^{[1
]}

Rolando, C ^{[1
]}

Tabourier, P ^{[1
]}

机构：

[1] IEMN, UMR 8520, F-59652 Villeneuve Dascq, France

来源：

MICROREATION TECHNOLOGY | 2001年

关键词：

D O I：

暂无

中图分类号：

TQ [化学工业];

学科分类号：

0817 ;

摘要：

We describe here our proposal for a microfluidic lab-on-chip devoted to protein identification by ESI/MS/MS. As a starting point we have realized silicon etched microchannels (10 mum depth) connected to a standard silicon needle. This elementary prototype ready for the sample mass spectrometer (MS) screening can be viewed as a first step before implementing basic functions as fluid actuation, Solid Phase Extraction (SPE) column, nanoemitter, necessary to cope with the nanospray problems.

引用

页码：572 / 578

页数：7

共 15 条

[1]

Desai A, 1997, TRANSDUCERS 97 - 1997 INTERNATIONAL CONFERENCE ON SOLID-STATE SENSORS AND ACTUATORS, DIGEST OF TECHNICAL PAPERS, VOLS 1 AND 2, P927, DOI 10.1109/SENSOR.1997.635254

[2] Tuning of an electrospray ionization source for maximum peptide-ion transmission into a mass spectrometer [J].