Respiratory Gated PET Derived in a Fully Automated Manner From Raw PET Data

被引:35
作者
Kesner, Adam Leon [1 ]
Bundschuh, Ralph Alexander [2 ]
Detorie, Nicole Christine [1 ]
Dahlbom, Magnus [1 ]
Ziegler, Sibylle Ilsa [2 ]
Czernin, Johannes [1 ]
Silverman, Daniel Hillel [1 ]
机构
[1] Univ Calif Los Angeles, Dept Pharmacol, Los Angeles, CA 90095 USA
[2] Tech Univ Munich, Klinikum Rechts Isar, Dept Nucl Med, D-81675 Munich, Germany
关键词
Fully automated; image-based; PET; respiratory gating; signal processing; software-based; ATTENUATION CORRECTION; MOTION CORRECTION; TUMOR MOTION; LUNG; REDUCTION; ARTIFACTS; CT; IMAGES;
D O I
10.1109/TNS.2009.2016341
中图分类号
TM [电工技术]; TN [电子技术、通信技术];
学科分类号
0808 ; 0809 ;
摘要
Respiratory motion in PET degrades image quality and limits detectability of small or low-contrast lesions. Although image quality can be improved using respiratory-gating, this adds to the complexity and expense of acquiring PET data. We aimed to develop a data-driven method, based on individual voxel signal fluctuations, for accomplishing electronic respiratory gating of clinical PET data, requiring no additional hardware or end-user input. We tested our methods using both simulated PET scans and actual human PET acquisitions. For the simulations, our methods correctly identified the start frame of each respiratory cycle defined for the phantom. Resultant gated images demonstrated improved effective resolution and increased measured uptake for lesions located in the thorax. For human PET data, we were able to recover respiratory phase information with a high signal-to-noise ratio. We report here a method to achieve fully automated voxel-based respiratory gating of PET images, without the need for gating hardware or additional user input, capable of improving effective resolution and increasing lesion detectability.
引用
收藏
页码:677 / 686
页数:10
相关论文
共 29 条
[1]   Consistency driven respiratory phase alignment and motion compensation in PET/CT [J].
Alessio, Adam ;
Kohlmyer, Steve ;
Kinahan, Paul .
2007 IEEE NUCLEAR SCIENCE SYMPOSIUM CONFERENCE RECORD, VOLS 1-11, 2007, :3115-+
[2]  
Boucher L, 2004, J NUCL MED, V45, P214
[3]   Postacquisition detection of tumor motion in the lung and upper abdomen using list-mode PET data:: A feasibility study [J].
Bundschuh, Ralph A. ;
Martinez-Moeller, Axel ;
Essler, Markus ;
Martinez, Maria-Josr ;
Nekolla, Stephan G. ;
Ziegler, Sibylle I. ;
Schwaiger, Markus .
JOURNAL OF NUCLEAR MEDICINE, 2007, 48 (05) :758-763
[4]   Optimization of super-resolution processing using incomplete image sets in PET imaging [J].
Chang, Guoping ;
Pan, Tinsu ;
Clark, John W., Jr. ;
Mawlawi, Osama R. .
MEDICAL PHYSICS, 2008, 35 (12) :5748-5757
[5]   Relation of external surface to internal tumor motion studied with cine CT [J].
Chi, Pai-Chun Melinda ;
Balter, Peter ;
Luo, Dershan ;
Mohan, Radhe ;
Pan, Tinsu .
MEDICAL PHYSICS, 2006, 33 (09) :3116-3123
[6]   Respiratory motion handling is mandatory to accomplish the high-resolution PET destiny [J].
Daou, Doumit .
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING, 2008, 35 (11) :1961-1970
[7]   Improved attenuation correction via appropriate selection of respiratory-correlated PET data [J].
Daouk, Joel ;
Fin, Loic ;
Bailly, Pascal ;
Meyer, Marc-Etienne .
COMPUTER METHODS AND PROGRAMS IN BIOMEDICINE, 2008, 92 (01) :90-98
[8]   Respiratory motion correction in 3-D PET data with advanced optical flow algorithms [J].
Dawood, Mohammad ;
Buether, Florian ;
Jiang, Xiaoyi ;
Schaefers, Klaus P. .
IEEE TRANSACTIONS ON MEDICAL IMAGING, 2008, 27 (08) :1164-1175
[9]  
Erdi YE, 2004, J NUCL MED, V45, P1287
[10]  
Feng B, 2005, IEEE NUCL SCI CONF R, P2173