Psychiatric Disorders in Adolescents Living with HIV and Association with Antiretroviral Therapy Adherence in Sub-Saharan Africa: A Systematic Review and Meta-analysis

被引：23

作者：

Olashore, Anthony A. ^{[1
]}

Paruk, Saeeda ^{[2
]}

Akanni, Oluyemi O. ^{[3
]}

Tomita, Andrew ^{[4
,5
]}

Chiliza, Bonginkosi ^{[2
]}

机构：

[1] Univ Botswana, Fac Med, Dept Psychiat, Gaborone, Botswana

[2] Univ KwaZulu Natal, Nelson R Mandela Sch Med, Dept Psychiat, Durban, South Africa

[3] Fed Neuropsychiat Hosp, Clin Serv, Benin, Edo State, Nigeria

[4] Univ KwaZulu Natal, KwaZulu Natal Res Innovat & Sequencing Platform, Nelson R Mandela Sch Med, Coll Hlth Sci, Durban, South Africa

[5] Univ KwaZulu Natal, Coll Hlth Sci, Ctr Rural Hlth, Durban, South Africa

来源：

AIDS AND BEHAVIOR | 2021年 / 25卷 / 06期

基金：

英国医学研究理事会;

关键词：

Adherence; Adolescents; HIV; Psychiatric disorders; Sub-Saharan Africa; CHILDRENS DEPRESSION INVENTORY; PERINATALLY ACQUIRED HIV; MENTAL-HEALTH; POSITIVE ADOLESCENTS; EXECUTIVE FUNCTION; INFECTED CHILDREN; HIV/AIDS; PERFORMANCE; PROGRESSION; PREVALENCE;

D O I：

10.1007/s10461-020-03100-z

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

In sub-Saharan Africa (SSA), a systematic approach to exploring the prevalence of psychiatric disorders (PDs) and adherence to antiretroviral treatment (ART) in adolescents living with HIV (ALWHIV) is lacking. This study aimed to systematically review the studies conducted in SSA on the prevalence of PDs among ALWHIV and their association with ART adherence. A systematic search of all English studies assessing PDs among ALWHIV using the Web of Science, PubMed, and EBSCO databases was conducted between March 1 and September 30, 2019. Forty-two studies published between 2009 to 2019 met the inclusion criteria, of which 15 were included in the meta-analysis. The most common PDs were depression (0.24, 95% CI 0.14-0.36) and anxiety disorder (0.26, 95% CI 2-0.44). The available evidence could not conclude on the definitive association between PDs and ART adherence; therefore, further research is required. However, the need for mental health integration in the care for ALWHIV is evident.

引用

页码：1711 / 1728

页数：18

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