NSAIDs and COVID-19: A New Challenging Area

被引：5
作者：
Baradaran, Hananeh [1 ]
Hamishehkar, Hadi [2 ]
Rezae, Haleh [2 ]
机构：
[1] Univ Tehran Med Sci, Dept Clin Pharm, Tehran, Iran
[2] Tabriz Univ Med Sci, Dept Clin Pharm, Tabriz, Iran
来源：
PHARMACEUTICAL SCIENCES | 2020年 / 26卷
关键词：
NSAIDs; COVID-19; Patients; NAPROXEN; NUCLEOPROTEIN; INDOMETHACIN; INFECTION;
D O I：
10.34172/PS.2020.41
中图分类号：
R9 [药学];
学科分类号：
1007 ;
摘要：
Considering the recent controversies regarding the use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs) in Coronavirus disease 2019 (COVID-19) patients, and due to the limited published data in this field, we reviewed currently available evidence for the use of NSAIDs in viral respiratory tract infections to help make decisions in this area. Currently, there is insufficient evidence to judge the safety and efficacy of NSAIDs in patients with COVID-19. According to the current evidence, acetaminophen is the choice treatment for symptomatic relief. If the patients' symptoms are not controlled by acetaminophen, naproxen may be used as an alternative therapy.
引用
收藏
页码：S49 / S51
页数：3
相关论文
共 26 条
[1]  
Amici C, 2006, ANTIVIR THER, V11, P1021
[2]   Inhibition of viral protein translation by indomethacin in vesicular stomatitis virus infection: role of eIF2 kinase PKR [J].
Amici, Carla ;
La Frazia, Simone ;
Brunelli, Claudia ;
Balsamo, Mirna ;
Angelini, Mara ;
Santoro, M. Gabriella .
CELLULAR MICROBIOLOGY, 2015, 17 (09) :1391-1404
[3]  
[Anonymous], 2020, BMJ-BRIT MED J, DOI DOI 10.1136/bmj.m1086
[4]   COVID-19: towards controlling of a pandemic [J].
Bedford, Juliet ;
Enria, Delia ;
Giesecke, Johan ;
Heymann, David L. ;
Ihekweazu, Chikwe ;
Kobinger, Gary ;
Lane, H. Clifford ;
Memish, Ziad ;
Oh, Myoung-don ;
Sall, Amadou Alpha ;
Schuchat, Anne ;
Ungchusak, Kumnuan ;
Wieler, Lothar H. .
LANCET, 2020, 395 (10229) :1015-1018
[5]   Vascular and upper gastrointestinal effects of non-steroidal anti-inflammatory drugs: meta-analyses of individual participant data from randomised trials [J].
Bhala, N. ;
Emberson, J. ;
Merhi, A. ;
Abramson, S. ;
Arber, N. ;
Baron, J. A. ;
Bombardier, C. ;
Cannon, C. ;
Farkouh, M. E. ;
FitzGerald, G. A. ;
Goss, P. ;
Halls, H. ;
Hawk, E. ;
Hawkey, C. ;
Hennekens, C. ;
Hochberg, M. ;
Holland, L. E. ;
Kearney, P. M. ;
Laine, L. ;
Lanas, A. ;
Lance, P. ;
Laupacis, A. ;
Oates, J. ;
Patrono, C. ;
Schnitzer, T. J. ;
Solomon, S. ;
Tugwell, P. ;
Wilson, K. ;
Wittes, J. ;
Baigent, C. ;
Adelowo, O. ;
Aisen, P. ;
Al-Quorain, A. ;
Altman, R. ;
Bakris, G. ;
Baumgartner, H. ;
Bresee, C. ;
Carducci, M. ;
Chang, D-M. ;
Chou, C-T. ;
Clegg, D. ;
Cudkowicz, M. ;
Doody, L. ;
El Miedany, Y. ;
Falandry, C. ;
Farley, J. ;
Ford, L. ;
GarciLosa, M. ;
Gonzalez-Ortiz, M. ;
Haghighi, M. .
LANCET, 2013, 382 (9894) :769-779
[6]   Covid-19: European drugs agency to review safety of ibuprofen [J].
Day, Michael .
BMJ-BRITISH MEDICAL JOURNAL, 2020, 368 :m1168
[7]   Are patients with hypertension and diabetes mellitus at increased risk for COVID-19 infection? [J].
Fang, Lei ;
Karakiulakis, George ;
Roth, Michael .
LANCET RESPIRATORY MEDICINE, 2020, 8 (04) :E21-E21
[8]   Efficacy of Clarithromycin-Naproxen-Oseltamivir Combination in the Treatment of Patients Hospitalized for Influenza A(H3N2) Infection An Open-label Randomized, Controlled, Phase IIb/III Trial [J].
Hung, Ivan F. N. ;
To, Kelvin K. W. ;
Chan, Jasper F. W. ;
Cheng, Vincent C. C. ;
Liu, Kevin S. H. ;
Tam, Anthony ;
Chan, Tuen-Ching ;
Zhang, Anna Jinxia ;
Li, Patrick ;
Wong, Tin-Lun ;
Zhang, Ricky ;
Cheung, Michael K. S. ;
Leung, William ;
Lau, Johnson Y. N. ;
Fok, Manson ;
Chen, Honglin ;
Chan, Kwok-Hung ;
Yuen, Kwok-Yung .
CHEST, 2017, 151 (05) :1069-1080
[9]   Non-steroidal anti-inflammatory drugs increase the antiretroviral activity of nucleoside reverse transcriptase inhibitors in HIV type-1-infected T-lymphocytes: role of multidrug resistance protein 4 [J].
Isabel Clemente, Ma ;
Alvarez, Susana ;
Jesus Serramia, Ma ;
Turriziani, Ombretta ;
Genebat, Miguel ;
Leal, Manuel ;
Fresno, Manuel ;
Angeles Munoz-Fernandez, Ma .
ANTIVIRAL THERAPY, 2009, 14 (08) :1101-1111
[10]  
Jia X, 2020, Preprints, DOI 10.20944/preprints202002.0315.v1
123