Molecular epidemiology and drug resistance of Acinetobacter baumannii isolated from a regional hospital in the Brazilian Amazon region

被引：5

作者：

Ribeiro, Edlainny Araujo ^{[1
]}

Gales, Ana Cristina ^{[2
]}

Streling de Oliveira, Ana Paula ^{[2
]}

Coelho, Danilo Dias ^{[3
]}

de Oliveira, Rodrigo Alves ^{[3
]}

Hoffmann Pfrimer, Irmtraut Araci ^{[1
]}

do Carmo Filho, Jose Rodrigues ^{[1
]}

机构：

[1] Pontificia Univ Catolica Goias, Programa Posgrad Stricto Sensu Ciencias Ambientai, Goiania, Go, Brazil

[2] Univ Fed Sao Paulo, Lab Especial Microbiol Clin, Sao Paulo, SP, Brazil

[3] Hosp Reg Publ Araguaia, Redencao, PA, Brazil

来源：

REVISTA DA SOCIEDADE BRASILEIRA DE MEDICINA TROPICAL | 2021年 / 54卷

关键词：

Acinetobacter baumannii; Carbapenem resistance; Carbapenemase; bla(OXA-23); Gram-negative bacilli;

D O I：

10.1590/0037-8682-0087-2020

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Introduction: In this study, we report a clonal dissemination of carbapenem resistant Acinetobacter baumannii isolates due to the acquisition of bla(OXA-23) in a regional hospital located in Brazilian Amazon Region. Methods: The isolates were identified by MALDI-TOF and the carbapenemase-encoding genes were detected by multiplex-PCR. The genetic similarity was investigated by pulsed-field gel electrophoresis (PFGE). Results: Only 10 (55.6%) isolates harbored the gene bla(OXA-23). PFGE analysis revealed that these isolates belong to a single clone. Conclusions: This dissemination strategy indicates the need for surveillance, adoption of control procedures defined in guidelines, and the careful administration of antimicrobials should be reinforced.

引用

页码：1 / 5

页数：5

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