Integrating sequence, evolution and functional genomics in regulatory genomics

被引：18

作者：

Vingron, Martin ^{[1
]}

Brazma, Alvis ^{[2
]}

Coulson, Richard ^{[2
]}

van Helden, Jacques ^{[3
]}

Manke, Thomas ^{[1
]}

Palin, Kimmo ^{[4
]}

Sand, Olivier ^{[3
]}

Ukkonen, Esko ^{[5
,6
]}

机构：

[1] Max Planck Inst Mol Genet, D-14195 Berlin, Germany

[2] European Bioinfomat Inst, Microarray Grp, Cambridge CB10 1SD, England

[3] Univ Libre Bruxelles, BiGRe, B-1050 Brussels, Belgium

[4] Wellcome Trust Sanger Inst, Cambridge CB10 1SA, England

[5] Aalto Univ, Helsinki Inst Informat Technol, Helsinki 00014, Finland

[6] Univ Helsinki, FIN-00014 Helsinki, Finland

来源：

GENOME BIOLOGY | 2009年 / 10卷 / 01期

关键词：

FACTOR-BINDING SITES; GENE-EXPRESSION; TARGET GENES; COMPUTATIONAL-DETECTION; SYSTEMATIC DISCOVERY; NONCODING SEQUENCES; IN-SILICO; ELEMENTS; DNA; IDENTIFICATION;

D O I：

10.1186/gb-2009-10-1-202

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

With genome analysis expanding from the study of genes to the study of gene regulation, 'regulatory genomics' utilizes sequence information, evolution and functional genomics measurements to unravel how regulatory information is encoded in the genome.

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页数：8

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