IssuesDespite a growing trend towards considering addiction as a chronic disease, the development of intervention models addressing the chronicity of substance use disorder is relatively new, and no literature review on this topic is available. The aim of this systematic review is to evaluate the efficacy of intervention models designed within the perspective of addiction as a chronic disease and those tailored to persons with substance use disorder who revolve in and out of treatment. ApproachElectronic databases were searched to identify articles published between 2000 and 2015 reporting an empirical study of an intervention model with data on its effectiveness. Study selection, data extraction and quality appraisal were performed independently by two reviewers. Key FindingsThe selection process yielded 16 studies meeting all the inclusion criteria. The intervention models were classified into four groups according to the duration, frequency and components of the interventions. In general, the models showed potential therapeutic effects. The outcomes tended to be positive immediately after the end of the treatment. However, months after, the benefits obtained during treatment did not persist. Implications and Conclusion.The review highlights that models designed specifically for persons with multiple treatment re-entries are scarce, but promising. Further research is needed to determine the best match between the clinical profile of persons with substance use disorder and a model's components, intensity and duration. [Simoneau H, Kamgang E, Tremblay J, Bertrand K, Brochu S, FleuryM-J. Efficacy of extensive interventionmodels for substance use disorders: A systematic review. Drug Alcohol Rev 2017;00:000-000]
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Univ Queensland, Sch Psychol, Lives Lived Well Res Grp, St Lucia Campus,Sir Fred Schonell Dr, St Lucia, Qld 4067, AustraliaUniv Queensland, Sch Psychol, Lives Lived Well Res Grp, St Lucia Campus,Sir Fred Schonell Dr, St Lucia, Qld 4067, Australia
de Andrade, Dominique
Elphinston, Rachel A.
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Univ Queensland, Sch Psychol, Lives Lived Well Res Grp, St Lucia Campus,Sir Fred Schonell Dr, St Lucia, Qld 4067, AustraliaUniv Queensland, Sch Psychol, Lives Lived Well Res Grp, St Lucia Campus,Sir Fred Schonell Dr, St Lucia, Qld 4067, Australia
Elphinston, Rachel A.
Quinn, Catherine
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Univ Queensland, Sch Psychol, Lives Lived Well Res Grp, St Lucia Campus,Sir Fred Schonell Dr, St Lucia, Qld 4067, AustraliaUniv Queensland, Sch Psychol, Lives Lived Well Res Grp, St Lucia Campus,Sir Fred Schonell Dr, St Lucia, Qld 4067, Australia
Quinn, Catherine
Allan, Julaine
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Univ Queensland, Sch Psychol, Lives Lived Well Res Grp, St Lucia Campus,Sir Fred Schonell Dr, St Lucia, Qld 4067, Australia
Lives Lived Well, Level 1-55 Little Edward St, Spring Hill, Qld 4000, AustraliaUniv Queensland, Sch Psychol, Lives Lived Well Res Grp, St Lucia Campus,Sir Fred Schonell Dr, St Lucia, Qld 4067, Australia
Allan, Julaine
Hides, Leanne
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Univ Queensland, Sch Psychol, Lives Lived Well Res Grp, St Lucia Campus,Sir Fred Schonell Dr, St Lucia, Qld 4067, AustraliaUniv Queensland, Sch Psychol, Lives Lived Well Res Grp, St Lucia Campus,Sir Fred Schonell Dr, St Lucia, Qld 4067, Australia
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Univ Michigan, Dept Psychiat, Bld 16,2nd Fl,2800 Plymouth Rd, Ann Arbor, MI 48109 USA
VA Ann Arbor Healthcare Syst, VA Ctr Clin Management Res, 2800 Plymouth Rd, Ann Arbor, MI 48109 USAUniv Michigan, Dept Psychiat, Bld 16,2nd Fl,2800 Plymouth Rd, Ann Arbor, MI 48109 USA
Lin, Lewei
Casteel, Danielle
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Univ Calif San Diego, Dept Family Med & Publ Hlth, Hlth Serv Res Ctr, 9500 Gilman Dr, La Jolla, CA 92093 USAUniv Michigan, Dept Psychiat, Bld 16,2nd Fl,2800 Plymouth Rd, Ann Arbor, MI 48109 USA
Casteel, Danielle
Shigekawa, Erin
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Univ Calif Berkeley, Calif Hlth Benefits Review Program, Berkeley, CA 94720 USAUniv Michigan, Dept Psychiat, Bld 16,2nd Fl,2800 Plymouth Rd, Ann Arbor, MI 48109 USA
Shigekawa, Erin
Weyrich, Meghan Soulsby
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Univ Calif Davis, Ctr Healthcare Policy & Res, 2103 Stockton Blvd, Sacramento, CA 95817 USAUniv Michigan, Dept Psychiat, Bld 16,2nd Fl,2800 Plymouth Rd, Ann Arbor, MI 48109 USA
Weyrich, Meghan Soulsby
Roby, Dylan H.
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Univ Maryland, Sch Publ Hlth, Dept Hlth Serv Adm, 4200 Valley Dr,Suite 3310, College Pk, MD 20742 USAUniv Michigan, Dept Psychiat, Bld 16,2nd Fl,2800 Plymouth Rd, Ann Arbor, MI 48109 USA
Roby, Dylan H.
McMenamin, Sara B.
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Univ Calif San Diego, Sch Med, Dept Family Med & Publ Hlth, 9500 Gilman Dr 0725, La Jolla, CA 92093 USAUniv Michigan, Dept Psychiat, Bld 16,2nd Fl,2800 Plymouth Rd, Ann Arbor, MI 48109 USA