Dealing with dangerous accidents: DNA double-strand breaks take centre stage Symposium on Genome Instability and DNA Repair

被引:5
作者
Costanzo, Vincenzo [1 ]
Chaudhuri, Jayanta [2 ]
Fung, Jennifer C. [3 ]
Moran, John V. [4 ,5 ]
机构
[1] London Res Inst, S Mimms EN6 3LD, Herts, England
[2] Mem Sloan Kettering Canc Ctr, Program Immunol, New York, NY 10021 USA
[3] Univ Calif San Francisco, Dept Obstet Gynecol & Reprod Sci, San Francisco, CA 94158 USA
[4] Univ Michigan, Sch Med, Dept Human Genet, Howard Hughes Med Inst, Ann Arbor, MI 48109 USA
[5] Univ Michigan, Sch Med, Dept Internal Med, Howard Hughes Med Inst, Ann Arbor, MI 48109 USA
关键词
copy-number variation; DNA repair; genome instability; non-homologous end joining; recombination; MEIOTIC RECOMBINATION; CHROMOSOMAL TRANSLOCATIONS; HOLLIDAY JUNCTION; STABILITY; ACTIVATION; DISORDERS; MECHANISM; BRCA1; EXO1; AID;
D O I
10.1038/embor.2009.173
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:837 / 842
页数:6
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