Prevalence of SARS-CoV-2 in Patients with Severe Pneumonia in Khuzestan Province, Iran

被引：6

作者：

Abolnezhadian, Farhad ^{[1
]}

Makvandi, Manoochehr ^{[2
]}

Alavi, Seyed Mohammad ^{[3
]}

Azaran, Azarakhsh ^{[2
]}

Jalilian, Shahram ^{[2
]}

Rashno, Mohammad ^{[4
]}

Kaydani, Gholam Abbas ^{[3
]}

Arshadi, Maniya ^{[5
]}

Hosseinizadeh, Seyed Mehdi ^{[6
]}

Boostani, Hatam ^{[7
]}

Seyedian, Seyed Saeed ^{[8
]}

Moogahi, Sasan ^{[9
]}

Salmanzadeh, Shokrolah ^{[9
]}

Varnaseri, Mehran ^{[9
]}

Neisi, Niloofar ^{[2
]}

Keifarrokhi, Hooman ^{[6
]}

Shariati, Gholamreza ^{[10
]}

Amiri, Homayoun ^{[6
]}

Parsanahad, Mehdi ^{[2
]}

Nashibi, Roohangiz ^{[9
]}

Yousefi, Farid ^{[9
]}

Ahmadi, Fatemeh ^{[9
]}

AhmadiAngali, Kambiz ^{[11
]}

机构：

[1] Ahvaz Jundishapur Univ Med Sci, Dept Allergy & Clin Immunol, Ahvaz, Iran

[2] Ahvaz Jundishapur Univ Med Sci, Dept Virol, Ahvaz, Iran

[3] Ahvaz Jundishapur Univ Med Sci, Infect & Trop Dis Res Ctr, Hlth Res Inst, Ahvaz, Iran

[4] Ahvaz Jundishapur Univ Med Sci, Fac Med, Dept Immunol, Ahvaz, Iran

[5] Ahvaz Jundishapur Univ Med Sci, Treatment, Ahvaz, Iran

[6] Ahvaz Jundishapur Univ Med Sci, Hlth, Ahvaz, Iran

[7] Ahvaz Jundishapur Univ Med Sci, Educ, Ahvaz, Iran

[8] Ahvaz Jundishapur Univ Med Sci, Golestan Hosp, Alimentary Tract Res Ctr, Ahvaz, Iran

[9] Ahvaz JundishapurUniv Med Sci, Sch Med, Dept Infect Dis, Ahvaz, Iran

[10] Ahvaz Jundishapur Univ Med Sci, Fac Med, Dept Med Genet, Ahvaz, Iran

[11] Ahvaz Jundishapur Univ Med Sci, Sch Hlth Sci, Dept Biostat & Epidemiol, Ahvaz, Iran

来源：

IRANIAN JOURNAL OF ALLERGY ASTHMA AND IMMUNOLOGY | 2020年 / 19卷 / 05期

关键词：

Nucleocapsid protein; Pneumonia; Real-time polymerase chain reaction; Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2); CORONAVIRUS; SARS; MERS; IDENTIFICATION; COV;

D O I：

10.18502/ijaai.v19i5.4462

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

The emergence of a highly pathogenic virus named severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) accounts for severe pneumonia throughout the world. More than 7 million world population have been infected with SARS-CoV-2, and the number of deaths is increasing every day. This study aimed to evaluate the frequency of SARS-CoV-2 in hospitalized patients with acute respiratory infection (ART). During an outbreak of the SARS-CoV-2, the nasopharyngeal and oropharyngeal swabs were collected from 909 hospitalized patients with severe pneumonia, including 517 (56.9%) males and 392 (43.1%) females. All the collected samples were from different cities of Khuzestan province from 19 February to- 27 March 2020. The RNA was extracted from samples and subjected to real-time polymerase chain reaction (PCR) tests for the detection of the SARS-CoV-2. Simultaneously, the computerized tomography (CT) scan was tested for the presence of ground-glass opacity in the lung among the patients. Of the total number of 909 specimens, 328 (36.08%) cases, including 185 (20.35%) females and 143 (15.73%) males, were positive for the SARS-CoV-2 while, 581 (63.9%) cases, including 374 (41.14%) males and 207 (22.77%) were negative for the SARS-CoV-2 by real-time PCR (p= 0.001).Four hundred sixteen (45.76%) cases were positive for ground-glass opacity in the lung by CT scan, while 328/909 (36.08%) trials proved positive for SARS-CoV-2 by the real-time PCR (p=0.003). In this study, 36.08% of patients were positive for SARS-CoV-2. Although the results of positive cases by CT scan showed higher than real-time PCR, screening the SARS-CoV-2 with a real-time PCR method is the first line of choice.

引用

页码：471 / 477

页数：7

共 43 条

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