Na+/Ca2+ exchange inhibitors: Potential drugs to mitigate the severity of ischemic injury

被引:18
作者
Akabas, MH
机构
[1] Yeshiva Univ Albert Einstein Coll Med, Dept Physiol & Biophys, Bronx, NY 10461 USA
[2] Yeshiva Univ Albert Einstein Coll Med, Dept Neurosci, Bronx, NY 10461 USA
关键词
D O I
10.1124/mol.104.000232
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:8 / 10
页数:3
相关论文
共 38 条
  • [1] Na+/H+ exchange inhibitors for cardioprotective therapy:: Progress, problems and prospects
    Avkiran, M
    Marber, MS
    [J]. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2002, 39 (05) : 747 - 753
  • [2] Resting membrane potential regulates Na+-Ca2+ exchange-mediated Ca2+ overload during hypoxia-reoxygenation in rat ventricular myocytes
    Baczkó, I
    Giles, WR
    Light, PE
    [J]. JOURNAL OF PHYSIOLOGY-LONDON, 2003, 550 (03): : 889 - 898
  • [3] Mechanisms underlying hypoxia-induced neuronal apoptosis
    Banasiak, KJ
    Xia, Y
    Haddad, GG
    [J]. PROGRESS IN NEUROBIOLOGY, 2000, 62 (03) : 215 - 249
  • [4] Sodium calcium exchange: Its physiological implications
    Blaustein, MP
    Lederer, WJ
    [J]. PHYSIOLOGICAL REVIEWS, 1999, 79 (03) : 763 - 854
  • [5] Effects of SEA0400 on mutant NCX1.1 Na+-Ca2+ exchangers with altered ionic regulation
    Bouchard, R
    Omelchenko, A
    Le, HD
    Choptiany, P
    Matsuda, T
    Baba, A
    Takahashi, K
    Nicoll, DA
    Philipson, KD
    Hnatowich, M
    Hryshko, LV
    [J]. MOLECULAR PHARMACOLOGY, 2004, 65 (03) : 802 - 810
  • [6] The vulnerable plaque and acute coronary syndromes
    Corti, R
    Farkouh, ME
    Badimon, JJ
    [J]. AMERICAN JOURNAL OF MEDICINE, 2002, 113 (08) : 668 - 680
  • [7] Co-localization of sodium channel Nav1.6 and the sodium-calcium exchanger at sites of axonal injury in the spinal cord in EAE
    Craner, MJ
    Hains, BC
    Lo, AC
    Black, JA
    Waxman, SG
    [J]. BRAIN, 2004, 127 : 294 - 303
  • [8] Overexpression of the cardiac Na+/Ca2+ exchanger increases susceptibility to ischemia/reperfusion injury in male, but not female, transgenic mice
    Cross, HR
    Lu, LY
    Steenbergen, C
    Philipson, KD
    Murphy, E
    [J]. CIRCULATION RESEARCH, 1998, 83 (12) : 1215 - 1223
  • [9] Inhibition of Na+/Ca2+ exchange by KB-R7943:: transport mode selectivity and antiarrhythmic consequences
    Elias, CL
    Lukas, A
    Shurraw, S
    Scott, J
    Omelchenko, A
    Gross, GJ
    Hnatowich, M
    Hryshko, LV
    [J]. AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY, 2001, 281 (03): : H1334 - H1345
  • [10] Na+/Ca2+ exchanger expression in the developing rat cortex
    Gibney, GT
    Zhang, JH
    Douglas, RM
    Haddad, GG
    Xia, Y
    [J]. NEUROSCIENCE, 2002, 112 (01) : 65 - 73