Vaccines against human enteric bacterial pathogens

被引：16

作者：

Dougan, G ^{[1
]}

Huett, A ^{[1
]}

Clare, S ^{[1
]}

机构：

[1] Univ London Imperial Coll Sci Technol & Med, Ctr Mol Microbiol & Infect, Dept Biol Sci, London SW7 2AZ, England

来源：

BRITISH MEDICAL BULLETIN | 2002年 / 62卷

关键词：

D O I：

10.1093/bmb/62.1.113

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The development of vaccines against enteric bacterial pathogens presents a challenge because of the large number of pathogens capable of causing disease and the requirement to induce immunity that is effective in the gut. A new generation of enteric vaccines based either on live or non-living antigens delivered orally or by injection are reaching the clinic in the early phases of evaluation. However, considerable technical barriers have to be overcome before these vaccines reach the general population.

引用

收藏

页码：113 / 123

页数：11

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