Multisystemic involvement in obstructive sleep apnea

被引：26
作者：
Labarca, Gonzalo [1 ]
Cruz N, Rodrigo [2 ]
Descalzi, Fernando [1 ]
机构：
[1] Univ Desarrollo, Clin Alemana, Santiago, Chile
[2] Univ Valparaiso, Hosp Dipreca Santiago, Valparaiso, Chile
来源：
REVISTA MEDICA DE CHILE | 2014年 / 142卷 / 06期
关键词：
Anoxia; Hypoventilation; Respiratory insufficiency; Sleep apnea; syndromes; POSITIVE AIRWAY PRESSURE; CARDIOVASCULAR-DISEASE; GASTROESOPHAGEAL-REFLUX; METABOLIC DYSFUNCTION; ASTHMA CONTROL; LIVER-INJURY; RISK-FACTORS; ASSOCIATION; PROGRESSION; MANAGEMENT;
D O I：
10.4067/S0034-98872014000600009
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Obstructive Sleep Apnea (OSA) is characterized by repetitive upper airway collapse with apnea/hypopnea and recurrent hypoxia during sleep, which results in fragmented sleep and intermittent drops in arterial blood oxygen saturation (hypoxemia). Several dysfunctions of neurocognitive, endocrine, cardiovascular, and metabolic systems are recognized in patients with OSA. The most commonly reported associations are with obesity, increased cardiovascular risk, dyslipidemia, diabetes mellitus 2 and liver damage. However, there is a proven relationship between OSA and other diseases, such as polycystic ovary syndrome, gastroesophageal reflux, and chronic kidney disease. The aim of this review is to analyze clinical and experimental evidence linking OSA with other diseases.
引用
收藏
页码：748 / 757
页数：10
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