m Microwave-Assisted Erlenmeyer Synthesis of Azlactones Catalyzed by MgO/Al2O3 Under Solvent-Free Conditions

被引：7

作者：

Rostamizadeh, Nader ^{[1
]}

Khajeh-Amiri, Alireza ^{[2
]}

Moghanian, Hassan ^{[1
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Dezful Branch, Dezful, Iran

[2] Islamic Azad Univ, Shahr E Rey Branch, Young Researchers & Elites Club, Tehran, Iran

来源：

SYNTHESIS AND REACTIVITY IN INORGANIC METAL-ORGANIC AND NANO-METAL CHEMISTRY | 2016年 / 46卷 / 05期

关键词：

azlactone; hippuric acid; MgO; Al2O3; microwave irradiation; solvent-free; ONE-POT SYNTHESIS; EFFICIENT METHOD; 4-ARYLIDENE-2-PHENYL-5(4H)-OXAZOLONES; 5-OXO-4,5-DIHYDRO-1,3-OXAZOLES; ACETATE; ACID;

D O I：

10.1080/15533174.2014.989575

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

MgO/Al2O3 catalyzes the synthesis of azlactone derivatives from condensation reaction of aldehydes (or ketones) with hippuric acid and acetic anhydride as a dehydrating agent under microwave irradiation. The low toxicity, low cost, ease of handling, and high activity of MgO/Al2O3 make this procedure particularly attractive. Also, this catalyst can be easily recovered by decant and can be reused for this condensation five times in succession without considerable loss of its catalytic activity.

引用

页码：631 / 634

页数：4

共 34 条

[1] Study on dry-media microwave azalactone synthesis on different supported KF catalysts:: influence of textural and acid-base properties of supports [J].

Bautista, FM ;

Campelo, JM ;

García, A ;

Luna, D ;

Marinas, JM ;

Romero, AA .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 2, 2002, 2 (02) :227-234

[2] CYCLIZATION OF ALPHA-ACYLAMINO-ACIDS IN PRESENCE OF PERCHLORIC-ACID TO GIVE 5-OXO-DELTA-2-OXAZOLINIUM PERCHLORATES [J].

BOYD, GV ;

WRIGHT, PH .

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1, 1972, (07) :909-&

[3] NEW SYNTHESIS OF THE CYCLIC TETRAPEPTIDE TENTOXIN EMPLOYING AN AZLACTONE AS KEY INTERMEDIATE [J].

CAVELIER, F ;

VERDUCCI, J .

TETRAHEDRON LETTERS, 1995, 36 (25) :4425-4428

[4]

CHEN FMF, 1979, SYNTHESIS-STUTTGART, P230

[5] A simple and efficient method for the synthesis of Erlenmeyer azlactones [J].

Conway, Philip A. ;

Devine, Kevin ;

Paradisi, Francesca .

TETRAHEDRON, 2009, 65 (15) :2935-2938

[6] MECHANISM AND EXTENSION OF THE FISCHER OXAZOLE SYNTHESIS [J].

CORNFORTH, JW ;

CORNFORTH, RH .

JOURNAL OF THE CHEMICAL SOCIETY, 1949, (APR) :1028-1030

[7]

DALLACROCE P, 1994, J CHEM SOC PERK T 1, P2499

[8]

Erlenmeyer E., 1893, LIEBIGS ANN CHEM, V275, P1

[9]

Etschenerg E., 1979, ETSCHENERG E, V2274, P55

[10]

Fischer E., 1896, BER DTSCH CHEM GES, V29, P205, DOI DOI 10.1002/CBER.18960290143

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