Antibiotic use and good practice in 314 French hospitals: The 2010 SPA2 prevalence study

被引：13

作者：

Alfandari, S. ^{[1
]}

Robert, J. ^{[2
]}

Pean, Y. ^{[3
]}

Rabaud, C. ^{[4
]}

Bedos, J. P. ^{[5
]}

Varon, E. ^{[6
]}

Lepape, A. ^{[7
]}

Bru, J. P. ^{[8
]}

Gauzit, R. ^{[9
]}

机构：

[1] Ctr Hosp Dron, Serv Reanimat & Malad Infect, F-59208 Tourcoing, France

[2] Hop Univ Pitie Salpetriere Charles Foix, AP HP, Bacteriol & Hyg, F-75013 Paris, France

[3] ONERBA, F-75006 Paris, France

[4] CHU, Serv Malad Infect, F-54511 Nancy, France

[5] Ctr Hosp Henri Mignot, Serv Reanimat, F-78157 Le Chesnay, France

[6] HEGP, Lab Bacteriol, F-75908 Paris, France

[7] Hop Sud, Serv Reanimat, F-69495 Lyon, France

[8] Ctr Hosp Reg Annecy, Serv Malad Infect, F-74374 Annecy, France

[9] CHU Cochin, AP HP, Serv Anesthesie Reanimat Chirurg, F-75679 Paris, France

来源：

MEDECINE ET MALADIES INFECTIEUSES | 2015年 / 45卷 / 11-12期

关键词：

Antibiotics; Audit; Antibiotic stewardship;

D O I：

10.1016/j.medmal.2015.10.001

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

Objectives. - We aimed to assess antibiotic prescriptions to identify potential targets for improvement. Methods. - We conducted a point prevalence survey (November 2010) of antibiotic use in 314 voluntary hospitals recruited by the French Infectious Diseases Society (SPILF) and the National Observatory for Epidemiology of Bacterial Resistance to Antimicrobials (ONERBA). Data were entered online, immediately analyzed and exported. Results. - The prevalence of antibiotic use was 19.5% (9059/46,446 patients). A higher prevalence was observed in the infectious disease (58.4%), hematology (58%), and intensive care (48.7%) units. The three most frequently used antibiotic classes were aminopenicillins (23.8%), fluoroquinolones (17.9%), and 3rd-generation cephalosporins (16.7%). A monotherapy was prescribed to 64% of patients. The reasons for the antibiotic prescription were written in the medical records of 74% of patients and 62% were consistent with the local guidelines. Conclusion. - Our results are similar to that of other studies. Various local targets for improvement have been identified to help hospitals define a better antibiotic stewardship. (C) 2015 Elsevier Masson SAS. All rights reserved.

引用

页码：475 / 480

页数：6