Preparation and Applications of Superparamagnetic Iron Oxide Nanoparticles in Novel Drug Delivery Systems: An Overview

被引：25

作者：

Hooshmand, Sara ^{[1
,2
]}

Hayat, Seyed Mohammad Gheibi ^{[3
]}

Ghorbani, Ahmad ^{[1
]}

Khatami, Mehrdad ^{[4
]}

Pakravanan, Kimya ^{[5
]}

Darroudi, Majid ^{[6
,7
]}

机构：

[1] Mashhad Univ Med Sci, Fac Med, Dept Pharmacol, Mashhad, Razavi Khorasan, Iran

[2] Mashhad Univ Med Sci, Fac Med, Pharmacol Res Ctr Med Plants, Mashhad, Razavi Khorasan, Iran

[3] Shahid Sadoughi Univ Med Sci, Sch Med, Dept Med Genet, Yazd, Iran

[4] Bam Univ Med Sci, NanoBloEletrochem Res Ctr, Bam, Iran

[5] Mashhad Univ Med Sci, Neurogen Inflammat Res Ctr, Mashhad, Razavi Khorasan, Iran

[6] Mashhad Univ Med Sci, Nucl Med Res Ctr, Mashhad, Razavi Khorasan, Iran

[7] Mashhad Univ Med Sci, Fac Med, Dept Modern Sci & Technol, Mashhad, Razavi Khorasan, Iran

来源：

CURRENT MEDICINAL CHEMISTRY | 2021年 / 28卷 / 04期

关键词：

Magnetic nanoparticles; size; shape; surface modification; functionalization; drug delivery; biocompatibility; biomedical applications; SILICA-MAGNETITE NANOCOMPOSITES; FE3O4; NANOPARTICLES; GREEN SYNTHESIS; PHASE MICROEXTRACTION; SURFACE MODIFICATION; CYTOTOXICITY; ACID; RESONANCE; SHELL; CORE;

D O I：

10.2174/0929867327666200123152006

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Nanocarriers, as drug delivery frameworks, have been intended to enhance the pharmacological and restorative properties of traditional medications. The consolidation of medical atoms as nanocarriers can function as the drug that is required against corruption, as well as offer the desired potential outcomes in regards to targeting and controlled discharge. In the present overview article, applications of magnetic nanoparticles (MNPs) in medication conveyance are outlined. The MNPs have increased the excitement due to their biocompatibility - low poisonous quality, and their capacity to be handled in a magnetic field, which enables their applications as drug-bearing vehicles. The simplicity of surface modification of these particles can provide opportunities for targeting the moieties that are linked to the particle surface. We trust that the intriguing particles will gain further attention alongside achievements in the current ones in the near future.

引用

页码：777 / 799

页数：23

共 122 条

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