NCCN Task Force Report: Bone Health in Cancer Care

被引：172

作者：

Gralow, Julie R. ^{[1
]}

Biermann, J. Sybil ^{[2
]}

Farooki, Azeez ^{[3
]}

Fornier, Monica N. ^{[3
]}

Gagel, Robert F. ^{[4
]}

Kumar, Rashmi N.

Shapiro, Charles L. ^{[5
]}

Shields, Andrew ^{[6
]}

Smith, Matthew R. ^{[7
]}

Srinivas, Sandy ^{[8
]}

Van Poznak, Catherine H. ^{[2
]}

机构：

[1] Fred Hutchinson Canc Res Ctr, Seattle, WA 98109 USA

[2] Univ Michigan, Ctr Comprehens Canc, Ann Arbor, MI 48109 USA

[3] Mem Sloan Kettering Canc Ctr, New York, NY 10021 USA

[4] Univ Texas MD Anderson Canc Ctr, Houston, TX 77030 USA

[5] Ohio State Univ, Ctr Comprehens Canc, James Canc Hosp, Columbus, OH 43210 USA

[6] Univ Washington, Med Ctr, Seattle, WA 98195 USA

[7] Massachusetts Gen Hosp, Boston, MA 02114 USA

[8] Stanford Comprehens Canc Ctr, Stanford, CA USA

来源：

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK | 2009年 / 7卷

关键词：

NCCN Clinical Practice Guidelines; bone health; breast cancer; prostate cancer; dual x-ray absorptiometry; bone mineral density; FRAX (TM) analysis; osteopenia; osteoporosis; bisphosphonates; aromatase inhibitors; chemotherapy; imaging; bone metastases; ANDROGEN-DEPRIVATION THERAPY; EARLY BREAST-CANCER; LONG-TERM EFFICACY; POSITRON-EMISSION-TOMOGRAPHY; HORMONE REPLACEMENT THERAPY; RANDOMIZED CONTROLLED-TRIAL; REFRACTORY PROSTATE-CANCER; ADVANCED MULTIPLE-MYELOMA; PLACEBO-CONTROLLED TRIAL; ORAL SODIUM CLODRONATE;

D O I：

10.6004/jnccn.2009.0076

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Bone health and maintenance of bone integrity are important components of comprehensive cancer care in both early and late stages of disease. Risk factors for osteoporosis are increased in patients with cancer, including women with chemotherapy-induced ovarian failure, those treated with aromatase inhibitors for breast cancer, men receiving androgen-deprivation therapy for prostate cancer, and patients undergoing glucocorticoid therapy. The skeleton is a common site of metastatic cancer recurrence, and skeletal-related events are the cause of significant morbidity. The National Comprehensive Cancer Network (NCCN) convened a multidisciplinary task force on Bone Health in Cancer Care to discuss the progress made in identifying effective screening and therapeutic options for management of treatment-related bone loss; understanding the factors that result in bone metastases; managing skeletal metastases; and evolving strategies to reduce bone recurrences. This report summarizes presentations made at the meeting. (JNCCN 2009;7[Suppl 3]:1-32)

引用

页码：S1 / S32

页数：32

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