A review of chromatographic methods for the determination of water- and fat-soluble vitamins in biological fluids

被引:27
作者
Karazniewicz-Lada, Marta [1 ]
Glowka, Anna [2 ]
机构
[1] Poznan Univ Med Sci, Dept Phys Pharm & Pharmacokinet, 6 Swiecickiego St, PL-60781 Poznan, Poland
[2] Poznan Univ Med Sci, Dept Bromatol, PL-60781 Poznan, Poland
关键词
Biological samples; Extraction; High-performance liquid chromatography; Vitamins; PERFORMANCE LIQUID-CHROMATOGRAPHY; TANDEM MASS-SPECTROMETRY; PRESSURE CHEMICAL-IONIZATION; SERUM 25-HYDROXYVITAMIN D-3; DIODE-ARRAY DETECTION; LC-MS/MS METHOD; HUMAN PLASMA; ALPHA-TOCOPHEROL; BETA-CAROTENE; D METABOLITES;
D O I
10.1002/jssc.201501038
中图分类号
O65 [分析化学];
学科分类号
070302 ; 081704 ;
摘要
Vitamins are an essential element of nutrition and thus contribute to human health. Vitamins catalyze many biochemical reactions and their lack or excess can cause health problems. Therefore, monitoring vitamin concentrations in plasma or other biological fluids may be useful in the diagnosis of various disorders as well as in the treatment process. Several chromatographic methods have been developed for the determination of these compounds in biological samples, including high-performance liquid chromatography with UV and fluorescence detection. Recently, high-performance liquid chromatography with tandem mass spectrometry methods have been widely used for the determination of vitamins in complex matrices because of their high sensitivity and selectivity. This method requires preconditioning of samples for analysis, including protein precipitation and/or various extraction techniques. The choice of method may depend on the desired cost, convenience, turnaround time, specificity, and accuracy of the information to be obtained. This article reviews the recently reported chromatographic methods used for determination of vitamins in biological fluids. Relevant papers published mostly during the last 5 years were identified by an extensive PubMed search using appropriate keywords. Particular attention was given to the preparation steps and extraction techniques. This report may be helpful in the selection of procedures that are appropriate for certain types of biological materials and analytes.
引用
收藏
页码:132 / 148
页数:17
相关论文
共 81 条
[1]  
Abano E. E., 2014, Croatian Journal of Food Science and Technology, V6, P116
[2]   Vitamins D and A can be successfully measured by LC-MS/MS in cord blood diluted plasma [J].
Albarhani, Ali A. ;
Collier, Fiona ;
Greaves, Ronda F. ;
Ponsonby, Anne-Louise ;
Allen, Katrina J. ;
Vuillermin, Peter J. ;
Roche, Peter ;
Clarke, Michael W. .
CLINICAL BIOCHEMISTRY, 2015, 48 (16-17) :1105-1112
[3]   Systematic review and meta-analysis of randomized placebo-controlled trials of folate and vitamin B12 for depression [J].
Almeida, Osvaldo P. ;
Ford, Andrew H. ;
Flicker, Leon .
INTERNATIONAL PSYCHOGERIATRICS, 2015, 27 (05) :727-737
[4]  
[Anonymous], 2008, CIRCULATION, DOI DOI 10.1161/CIRCULATIONAHA.107.706127
[5]   Unexpected high plasma cobalamin [J].
Arendt, Johan F. B. ;
Nexo, Ebba .
CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2013, 51 (03) :489-496
[6]   A sensitive and specific method for measurement of multiple retinoids in human serum with UHPLC-MS/MS [J].
Arnold, Samuel L. M. ;
Amory, John K. ;
Walsh, Thomas J. ;
Isoherranen, Nina .
JOURNAL OF LIPID RESEARCH, 2012, 53 (03) :587-598
[7]   HPLC method for plasma vitamin K1:: Effect of plasma triglyceride and acute-phase response on circulating concentrations [J].
Azharuddin, Mohammed K. ;
O'Reilly, Denis St. J. ;
Gray, Andrew ;
Talwar, Dinesh .
CLINICAL CHEMISTRY, 2007, 53 (09) :1706-1713
[8]   Simultaneous quantification of four vitamin D metabolites in human serum using high performance liquid chromatography tandem mass spectrometry for vitamin D profiling [J].
Baecher, Silvia ;
Leinenbach, Andreas ;
Wright, Jo Anne ;
Pongratz, Stephan ;
Kobold, Uwe ;
Thiele, Roland .
CLINICAL BIOCHEMISTRY, 2012, 45 (16-17) :1491-1496
[9]   Ultra-Performance Liquid Chromatographic Determination of Tocopherols and Retinol in Human Plasma [J].
Bell, Edward C. ;
John, Mathew ;
Hughes, Rodney J. ;
Thu Pham .
JOURNAL OF CHROMATOGRAPHIC SCIENCE, 2014, 52 (09) :1065-1070
[10]   Selective extraction and determination of vitamin B12 in urine by ionic liquid-based aqueous two-phase system prior to high-performance liquid chromatography [J].
Berton, Paula ;
Monasterio, Romina P. ;
Wuilloud, Rodolfo G. .
TALANTA, 2012, 97 :521-526