Recent Development in the Synthesis of Natural Saponins and Their Derivatives

被引：20
作者：
Zu, Luning [1 ]
Zhao, Yisheng [2 ]
Gu, Guofeng [2 ]
机构：
[1] PLA 404 Hosp, Weihai 264200, Shandong, Peoples R China
[2] Shandong Univ, Natl Glycoengn Res Ctr, Jinan 250010, Peoples R China
来源：
JOURNAL OF CARBOHYDRATE CHEMISTRY | 2014年 / 33卷 / 06期
基金：
国家高技术研究发展计划(863计划);
关键词：
Saponin; Chemical synthesis; Biological activity; PROTECTED GLYCOSYL DONORS; OLEANOLIC ACID; FACILE SYNTHESIS; CYTOTOXIC ACTIVITIES; ANTITUMOR ACTIVITIES; TRITERPENOID SAPONINS; BIOLOGICAL EVALUATION; STEROIDAL GLYCOSIDES; HELICOBACTER-PYLORI; EFFICIENT SYNTHESIS;
D O I：
10.1080/07328303.2014.957387
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
Naturally occurring saponins are attractive candidates or lead compounds for new drug design and development and thus have become important synthetic targets. This short account reviews the recent progress in the chemical synthesis and structure-activity relationship (SAR) studies of naturally occurring saponins and their derivatives.
引用
收藏
页码：269 / 297
页数：29
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