Facile synthesis of novel fluorescent organosilica-coated MOF nanoparticles for fast curcumin adsorption

Nano metal-organic framework materials are progressively being investigated and used as drug carriers in the biomedical field. Curcumin, an active component derived from turmeric, is commonly utilized in traditional medicine and can support cancer treatment. In this study, ZIF-8 nanomaterial was effectively modified with fluorescence organosilica coating, named ZIF-8@BPMO, to promote bio-interaction and prevent material flocculation. Powder X-ray diffraction (PXRD), infrared spectroscopy (FT-IR), differential gravimetric analysis (TGA), and isothermal nitrogen adsorption at 77 K were utilized to investigate the synthesized materials. Property analysis revealed that ZIF-8@BPMO nanomaterials had high crystallinity, a large surface area, and a high thermal stability with a particle size of 100 nm. According to the research, this material had high curcumin adsorption capacity of 666 mg g(-1) for 15 min. Curcumin adsorption on the nanomaterial followed a pseudosecond-order kinetic model and the Freundlich model. Furthermore, thermodynamic investigations demonstrated an endothermic and spontaneous adsorption mechanism. These results indicate that the fluorescent ZIF8@BPMO nanoparticle is a potential material for bio-applications.