Cellular and molecular basis of heavy metal-induced stress in ciliates

被引：15

作者：

Somasundaram, Sripoorna ^{[1
]}

Abraham, Jeeva Susan ^{[1
]}

Maurya, Swati ^{[1
]}

Makhija, Seema ^{[1
]}

Gupta, Renu ^{[2
]}

Toteja, Ravi ^{[1
]}

机构：

[1] Univ Delhi, Acharya Narendra Dev Coll, Ciliate Biol Lab, New Delhi 110019, India

[2] Univ Delhi, Maitreyi Coll, Bapudham Complex, New Delhi 110021, India

来源：

CURRENT SCIENCE | 2018年 / 114卷 / 09期

关键词：

Ciliates; heat shock protein; heavy metal stress; metallothionein; superoxide dismutase; FRESH-WATER CILIATE; METALLOTHIONEIN GENE; SHOCK PROTEINS; INDUCIBLE METALLOTHIONEIN; TETRAHYMENA-PYRIFORMIS; ACUTE TOXICITY; EXPRESSION ANALYSIS; OXIDATIVE STRESS; PLANT-RESPONSES; WASTE-WATER;

D O I：

10.18520/cs/v114/i09/1858-1865

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Globally, heavy metals are the major pollutants present in both terrestrial and aquatic ecosystems. Increase in their concentration due to various anthropogenic activities is a matter of concern. Higher concentration of these metals is known to be toxic due to their non-biodegradable nature. Eukaryotic microorganisms, ciliates can be used as cellular tools to assess and study the various mechanisms to overcome heavy metal toxicity. Here we discuss, at cellular level, the effect of heavy metal toxicity on growth rate, behavioural and morphological changes of ciliates. At the molecular level, changes in stress genes like hsp70, metallothionein and expression of various antioxidant enzymes (superoxide dismutase, glutathione peroxidase) adopted by ciliates have also been deliberated. It is also being argued that ciliates can be used as biosensor/cellular tools for detecting heavy metal pollution.

引用

页码：1858 / 1865

页数：8

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